» Articles » PMID: 34901489

A Review on the Traditional Uses, Phytochemistry, and Pharmacological Activities of Clove Basil ( L.)

Overview
Journal Heliyon
Specialty Social Sciences
Date 2021 Dec 13
PMID 34901489
Citations 18
Authors
Affiliations
Soon will be listed here.
Abstract

In traditional medicine, (clove basil) is used in the treatment of various diseases such as diabetes, cancer, inflammation, anaemia, diarrhoea, pains, and fungal and bacterial infections. The present study reviewed the phytochemicals, essential oils, and pharmacological activities of . The bioactive compounds extracted from include phytochemicals (oleanolic acid, caffeic acid, ellagic acid, epicatechin, sinapic acid, rosmarinic acid, chlorogenic acid, luteolin, apigenin, nepetoidin, xanthomicrol, nevadensin, salvigenin, gallic acid, catechin, quercetin, rutin, and kaempfero) and essential oils (camphene, β-caryophyllene, α- and β-pinene, α-humulene, sabinene, β-myrcene, limonene, 1,8-cineole, trans-β-ocimene, linalool, α- and δ-terpineol, eugenol, α-copaene, β-elemene, p-cymene, thymol, and carvacrol). Various and studies have shown that and its bioactive constituents possess pharmacological properties such as antioxidant, anti-inflammatory, anticancer, hepatoprotective, antidiabetic, antihypertensive, antidiarrhoeal, and antimicrobial properties. This review demonstrated that has a strong preventive and therapeutic effect against several diseases. The effectiveness of to ameliorate various diseases may be attributed to its antimicrobial and antioxidant properties as well as its capacity to improve the antioxidant systems. However, despite the widespread pharmacological activities of , further experiments in human clinical trial studies are needed to establish effective and safe doses for the treatment of various diseases.

Citing Articles

Inclusion of antimicrobial and antioxidant spices into milk candy towards enhancement of nutrient contents and bio-functional activities.

Faturoti A, Ogidi C Heliyon. 2025; 11(3):e42249.

PMID: 39959487 PMC: 11830343. DOI: 10.1016/j.heliyon.2025.e42249.


Unveiling the apoptotic potential of antioxidant-rich Bangladeshi medicinal plant extractives and computational modeling to identify antitumor compounds.

Haque M, Alam A, Islam Shovon M, Sujon K, Hasan Maruf M, Kabir S Heliyon. 2024; 10(20):e38885.

PMID: 39492885 PMC: 11531630. DOI: 10.1016/j.heliyon.2024.e38885.


Impact of Microencapsulation on L. Essential Oil: Antimicrobial, Antioxidant Activities, and Chemical Composition.

Granados A, Duarte M, Noguera N, Lima D, Rodrigues R Foods. 2024; 13(19).

PMID: 39410158 PMC: 11476232. DOI: 10.3390/foods13193122.


REMP: A unique dataset of rare and endangered medicinal plants in Bangladesh for sustainable healing and biodiversity conservation.

Islam M, Rahman S, Hoque N, Mamun M, Moheuddin M, Ali M Data Brief. 2024; 57:110895.

PMID: 39314890 PMC: 11418000. DOI: 10.1016/j.dib.2024.110895.


Attenuation of PI3K/AKT signaling pathway by leaf flavonoid-rich extracts in streptozotocin-induced diabetic male rats.

Ajiboye B, Famusiwa C, Amuda M, Afolabi S, Ayotunde B, Adejumo A Biochem Biophys Rep. 2024; 38:101735.

PMID: 38799115 PMC: 11127474. DOI: 10.1016/j.bbrep.2024.101735.


References
1.
Paula-Freire L, Andersen M, Molska G, Kohn D, Carlini E . Evaluation of the antinociceptive activity of Ocimum gratissimum L. (Lamiaceae) essential oil and its isolated active principles in mice. Phytother Res. 2012; 27(8):1220-4. DOI: 10.1002/ptr.4845. View

2.
Ileke K, Adesina J . Toxicity of and Extracts against Main Malaria Vector, (Diptera: Culicidae) in Nigeria. J Arthropod Borne Dis. 2020; 13(4):362-368. PMC: 7188766. View

3.
Tsai S, Yin M . Antioxidative and anti-inflammatory protection of oleanolic acid and ursolic acid in PC12 cells. J Food Sci. 2008; 73(7):H174-8. DOI: 10.1111/j.1750-3841.2008.00864.x. View

4.
Hassan S, Gali-Muhtasib H, Goransson H, Larsson R . Alpha terpineol: a potential anticancer agent which acts through suppressing NF-kappaB signalling. Anticancer Res. 2010; 30(6):1911-9. View

5.
Tohidi B, Rahimmalek M, Arzani A, Trindade H . Sequencing and variation of terpene synthase gene (TPS2) as the major gene in biosynthesis of thymol in different Thymus species. Phytochemistry. 2019; 169:112126. DOI: 10.1016/j.phytochem.2019.112126. View