Phosphorylation of Histone H2A at Serine 95 Is Essential for Flowering Time and Development in

Overview

Journal Front Plant Sci

Date 2021 Dec 10

PMID 34887889

Citations 1

Authors

Tongtong Huang

Heng Zhang

Yiming Zhou

Yanhua Su

Han Zheng

Yong Ding

Affiliations

Soon will be listed here.

Abstract

Phosphorylation of H2A at serine 95 (H2AS95ph) mediated by MLK4 promotes flowering and H2A.Z deposition. However, little is known about MLK1, MLK2, and MLK3 during the flowering time. Here, we systemically analyze the functions of MLK family in flowering time and development. Mutation in , but not and , displayed late-flowering phenotype. Loss of function enhanced the late-flowering phenotype of mutant, but not reinforced the late-flowering phenotype of double mutants. MLK3 displayed the kinase activity to histone H2AS95ph . The global H2AS95ph levels were reduced in , but not in and single mutant and double mutant, and the H2AS95ph levels in and were similar to those in double mutant. MLK3 interacted with CCA1, which binds to the promoter of . Correspondingly, the transcription levels and H2AS95ph levels of were reduced in and single mutant, and greatly decreased in double mutant, but not further attenuated in and triple mutant. Together, our results suggested that H2AS95ph deposition mediated by MLK3 and MLK4 is essential for flowering time in .

Citing Articles

Post-Translational Modifications in Histones and Their Role in Abiotic Stress Tolerance in Plants.

Sharma M, Sidhu A, Samota M, Gupta M, Koli P, Choudhary M Proteomes. 2023; 11(4).

PMID: 38133152 PMC: 10747722. DOI: 10.3390/proteomes11040038.

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