Sensitization Profiles of Timothy Grass Pollen in Northern China

Overview

Journal J Asthma Allergy

Publisher Dove Medical Press

Date 2021 Dec 8

PMID 34876820

Citations 4

Authors

Yingyang Xu

Kai Guan

Li Sha

Jinghong Zhang

Yongliang Niu

Jia Yin

Lianglu Wang

Affiliations

Soon will be listed here.

Abstract

Purpose: Grass pollen is an important cause of IgE-mediated allergy in countries worldwide, especially within Europe. However, there has been no research on grass pollen allergy in northern China. We aimed to determine the status of grass pollen allergy and the sensitization patterns to () in northern China.

Patients And Methods: Pollen data were collected for three geographic areas (Beijing, Shenmu, Shizuishan) in northern China. The study enrolled 101 patients (62 men; age range, 1-64 years; median age, 10 years) who had allergic rhinoconjunctivitis and/or asthma during the grass pollen season and positive skin prick test results positive to . Serum-specific IgE (sIgE) against Phl p 1, Phl p 2, Phl p 5, Phl p 6, Phl p 7, Phl p 12 was measured by ImmunoCAP.

Results: The pollen season of was from June to September in Beijing, May to September in Shenmu and July to August in Shizuishan. pollen accounted for 2-3% of the annual pollen index of total pollen counts. Among 101 patients with positive skin prick test results to , 72% had detectable sIgE to . Phl p 12 was the most frequently recognized component (45%), followed by Phl p 1 (22%), Phl p 5 (14%), Phl p 6 (8%) and Phl p 7 (3%). No patients had sIgE to Phl p 2. Ten sensitization patterns to the six components were observed. High rate of sIgE to Phl p 12 was positively correlated with co-sensitization to weed or tree pollen.

Conclusion: Considering the pollen concentration, was a minor pollen allergen in northern China and its pollen season overlapped with that of weed pollen. IgE sensitization to was likely to be induced by cross-reactivity between grass pollen allergy and weed/tree pollen allergy.

Citing Articles

Profile of cross-reactivity to common pollen allergens in Northwest China based on component resolved diagnosis.

Li A, Huang Z, Ye Q, Zheng X, Zhang J, Chen T Sci Rep. 2024; 14(1):24446.

PMID: 39424620 PMC: 11489645. DOI: 10.1038/s41598-024-73465-x.

Incidence of grass and weed sensitization in Bangkok, Thailand: a clinical study.

Aud-In S, Juprasong Y, Pinkaew B, Talek K, Tantilipikorn P, Songnuan W Front Public Health. 2024; 12:1301095.

PMID: 38605873 PMC: 11007029. DOI: 10.3389/fpubh.2024.1301095.

Sensitization patterns to Poaceae pollen indicates a hierarchy in allergens and a lead of tropical grasses.

Rodinkova V, Yuriev S, Mokin V, Sharikadze O, Kryzhanovskyi Y, Kremenska L Clin Transl Allergy. 2023; 13(8):e12287.

PMID: 37632241 PMC: 10405149. DOI: 10.1002/clt2.12287.

Common Allergens and Immune Responses Associated with Allergic Rhinitis in China.

Li Q, Zhang X, Feng Q, Zhou H, Ma C, Lin C J Asthma Allergy. 2023; 16:851-861.

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