Deregulation of Ribosomal Proteins in Human Cancers

Overview

Journal Biosci Rep

Specialty Cell Biology

Date 2021 Dec 7

PMID 34873618

Citations 38

Authors

Wendy El Khoury

Zeina Nasr

Affiliations

Soon will be listed here.

Abstract

The ribosome, the site for protein synthesis, is composed of ribosomal RNAs (rRNAs) and ribosomal proteins (RPs). The latter have been shown to have many ribosomal and extraribosomal functions. RPs are implicated in a variety of pathological processes, especially tumorigenesis and cell transformation. In this review, we will focus on the recent advances that shed light on the effects of RPs deregulation in different types of cancer and their roles in regulating the tumor cell fate.

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