Triple-enzyme Mimetic Activity of FeO@C@MnO Composites Derived from Metal-organic Frameworks and Their Application to Colorimetric Biosensing of Dopamine

Overview

Journal Mikrochim Acta

Specialties Biotechnology
Chemistry

Date 2021 Dec 6

PMID 34866160

Citations 3

Authors

Yanyan Xing

Meiling Chen

Yunkun Zhao

Jiabi Xu

Xiaohong Hou

Affiliations

Soon will be listed here.

Abstract

Novel FeO@C@MnO composites were successfully synthesized for the first time via an interfacial reaction between magnetic porous carbon and KMnO, in which the magnetic porous carbon was derived from the pyrolysis of Fe-MIL-88A under N atmosphere. Interestingly, the obtained FeO@C@MnO composites were found to have triple-enzyme mimetic activity including peroxidase-like, catalase-like, and oxidase-like activity. As a peroxidase mimic, FeO@C@MnO composites could catalyze the oxidation of TMB into a blue oxidized product by HO. As a catalase mimic, FeO@C@MnO could catalyze the decomposition of HO to generate O and HO. As an oxidase mimic, FeO@C@MnO could catalyze the direct oxidation of TMB to produce a blue oxidized product without HO. Reactive oxygen species measurements revealed that the oxidase-like activity originated from O and O∙and little∙OH generated by the dissolved oxygen, which was catalyzed by the FeO@C@MnO in the TMB oxidation reaction. The oxidase-like activity of FeO@C@MnO was investigated in detail. Under the optimized conditions, a rapid, sensitive, visual colorimetric method for dopamine detection was developed based on the inhibitory effect of dopamine on the oxidase-like activity. The proposed method allows for dopamine detection with a limit of detection of 0.034 μM and a linear range of 0.125-10 μM. This new colorimetric method was successfully used for the determination of dopamine in human blood samples.

Citing Articles

A Multi-Enzyme Cascade Response for the Colorimetric Recognition of Organophosphorus Pesticides Utilizing Core-Shell Pd@Pt Nanoparticles with High Peroxidase-like Activity.

Majid Z, Zhang Q, Yang Z, Che H, Cheng N Foods. 2023; 12(17).

PMID: 37685251 PMC: 10486685. DOI: 10.3390/foods12173319.

Synthesis of TiCT /MnO composites for synergistic catalytic/photothermal-based bacterial inhibition.

Hu T, Xu Z, Zhang P, Fan L, Xi J, Han J Nanoscale Adv. 2023; 5(8):2216-2225.

PMID: 37056616 PMC: 10089122. DOI: 10.1039/d2na00923d.

In Situ Synthesis of a BiTe-Nanosheet/Reduced-Graphene-Oxide Nanocomposite for Non-Enzymatic Electrochemical Dopamine Sensing.

Shen H, Jang B, Park J, Mun H, Cho H, Choa Y Nanomaterials (Basel). 2022; 12(12).

PMID: 35745351 PMC: 9228124. DOI: 10.3390/nano12122009.

References

Aziz A, Asif M, Azeem M, Ashraf G, Wang Z, Xiao F . Self-stacking of exfoliated charged nanosheets of LDHs and graphene as biosensor with real-time tracking of dopamine from live cells. Anal Chim Acta. 2018; 1047:197-207. DOI: 10.1016/j.aca.2018.10.008. View

Zanetti C, Spitz S, Berger E, Bolognin S, Smits L, Crepaz P . Monitoring the neurotransmitter release of human midbrain organoids using a redox cycling microsensor as a novel tool for personalized Parkinson's disease modelling and drug screening. Analyst. 2021; 146(7):2358-2367. DOI: 10.1039/d0an02206c. View

Nath I, Chakraborty J, Verpoort F . Metal organic frameworks mimicking natural enzymes: a structural and functional analogy. Chem Soc Rev. 2016; 45(15):4127-70. DOI: 10.1039/c6cs00047a. View

Wei H, Wang E . Fe3O4 magnetic nanoparticles as peroxidase mimetics and their applications in H2O2 and glucose detection. Anal Chem. 2008; 80(6):2250-4. DOI: 10.1021/ac702203f. View

Lin T, Zhong L, Song Z, Guo L, Wu H, Guo Q . Visual detection of blood glucose based on peroxidase-like activity of WS2 nanosheets. Biosens Bioelectron. 2014; 62:302-7. DOI: 10.1016/j.bios.2014.07.001. View

Zheng A, Cong Z, Wang J, Li J, Yang H, Chen G . Highly-efficient peroxidase-like catalytic activity of graphene dots for biosensing. Biosens Bioelectron. 2013; 49:519-24. DOI: 10.1016/j.bios.2013.05.038. View

Su L, Qin W, Zhang H, Rahman Z, Ren C, Ma S . The peroxidase/catalase-like activities of MFe₂O₄ (M=Mg, Ni, Cu) MNPs and their application in colorimetric biosensing of glucose. Biosens Bioelectron. 2014; 63:384-391. DOI: 10.1016/j.bios.2014.07.048. View

Zhang X, Han G, Zhang R, Huang Z, Shen H, Su P . CoVO Particles with Intrinsic Multienzyme Mimetic Activities as an Effective Bioplatform for Ultrasensitive Fluorometric and Colorimetric Biosensing. ACS Appl Bio Mater. 2022; 3(3):1469-1480. DOI: 10.1021/acsabm.9b01107. View

Chen S, Wang Y, Zhong M, Yu D, Wang C, Lu X . Fe(III)-Tannic Acid Complex Derived FeC Decorated Carbon Nanofibers for Triple-Enzyme Mimetic Activity and Their Biosensing Application. ACS Biomater Sci Eng. 2021; 5(3):1238-1246. DOI: 10.1021/acsbiomaterials.8b01552. View

10.

Wang Y, Zhu Y, Binyam A, Liu M, Wu Y, Li F . Discovering the enzyme mimetic activity of metal-organic framework (MOF) for label-free and colorimetric sensing of biomolecules. Biosens Bioelectron. 2016; 86:432-438. DOI: 10.1016/j.bios.2016.06.036. View

11.

Duan B, Wang D, Wu H, Xu P, Jiang P, Xia G . Core-Shell Structurized FeO@C@MnO Nanoparticles as pH Responsive T-T* Dual-Modal Contrast Agents for Tumor Diagnosis. ACS Biomater Sci Eng. 2021; 4(8):3047-3054. DOI: 10.1021/acsbiomaterials.8b00287. View