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Marburg Multiple Sclerosis Variant: Complete Remission with Very Early Administration of Mitoxantrone-A Case Report

Overview
Journal Neurol Ther
Publisher Springer
Specialty Neurology
Date 2021 Dec 3
PMID 34859363
Citations 3
Authors
Nicolas Capet
Michael Levraut
Adrien Delourme
Oceane Thomel-Rocchi
Veronique Bourg
Philippe Cabre
Fanny Vandenbos
Lydiane Mondot
Christine Lebrun-Frenay
Affiliations
Soon will be listed here.
Abstract

Marburg variant is a severe and fulminant pseudotumor form of multiple sclerosis (MS) with high morbidity and mortality rates. Because of its scarcity, it remains incompletely characterized and physicians' experiences will influence the treatment. We report the inflammatory explosive case of a 31-year-old woman presenting with rapid neurological degradation of histology proven Marburg's disease, successfully treated with early administration of Mitoxantrone (MITX). To our knowledge, it is the first case describing complete remission after MITX in a biopsy-proven condition.

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