Quality-adjusted Life Year Comparison at Medium Term Follow-up of Endovascular Versus Open Surgical Repair for Abdominal Aortic Aneurysm in Young Patients

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2021 Dec 2

PMID 34855851

Citations 1

Authors

Eunae Byun

Tae-Won Kwon

Hyangkyoung Kim

Yong Pil Cho

Youngjin Han

Gi Young Ko

Min-Jae Jeong

Affiliations

Soon will be listed here.

Abstract

Objectives: This study aimed to compare the quality of life and cost effectiveness between endovascular aneurysm repair (EVAR) and open surgical repair (OSR) in young patients with abdominal aortic aneurysm (AAA).

Design: This was a single-center, observational, and retrospective study.

Materials And Methods: A retrospective analysis was conducted of patients with AAA, who were <70 years old and underwent EVAR or OSR between January 2012 and October 2016. Only patients with aortic morphology that was suitable for EVAR were enrolled. Data on the complication rates, medical expenses, and expected quality-adjusted life years (QALYs) were collected, and the cost per QALY at three years was compared.

Results: Among 90 patients with aortic morphology who were eligible for EVAR, 37 and 53 patients underwent EVAR and OSR, respectively. No significant differences were observed in perioperative cardiovascular events and death between the two groups. However, during the follow-up period, patients undergoing OSR showed a significantly lower complication rate (hazard ratio [HR] = 0.11; P = .021). From the three-year cost-effectiveness analysis, the total sum of costs was significantly lower in the OSR group (P < .001) than that in the EVAR group, and the number of QALYs was superior in the OSR group (P = .013). The cost per QALY at three years was significantly lower in the OSR group than that in the EVAR group (mean: $4038 vs. $10 137; respectively; P < .001).

Conclusions: OSR had lower complication rates and better cost-effectiveness than EVAR Among young patients with feasible aortic anatomy.

Citing Articles

Treatment of abdominal aortic aneurysms in Korea: a nationwide study.

Kim H, Kwon T, Cho Y, Gwon J, Han Y, Lee S Ann Surg Treat Res. 2023; 105(1):37-46.

PMID: 37441324 PMC: 10333808. DOI: 10.4174/astr.2023.105.1.37.

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