Resident Macrophages in the Heart: Cardioprotective Under Pressure

Overview

Journal Circ Res

Specialty Cardiology & Vascular Diseases

Date 2021 Dec 2

PMID 34855465

Citations 4

Authors

Mohamed Ameen Ismahil

Sumanth D Prabhu

Affiliations

Soon will be listed here.

Citing Articles

Pathophysiology of Angiotensin II-Mediated Hypertension, Cardiac Hypertrophy, and Failure: A Perspective from Macrophages.

Carter K, Shah E, Waite J, Rana D, Zhao Z Cells. 2024; 13(23).

PMID: 39682749 PMC: 11640308. DOI: 10.3390/cells13232001.

Myocardial Inflammation in Heart Failure With Reduced and Preserved Ejection Fraction.

Alcaide P, Kallikourdis M, Emig R, Prabhu S Circ Res. 2024; 134(12):1752-1766.

PMID: 38843295 PMC: 11160997. DOI: 10.1161/CIRCRESAHA.124.323659.

ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice.

Zhuang T, Chen M, Wu R, Wang J, Hu X, Meng T Nat Commun. 2024; 15(1):1995.

PMID: 38443404 PMC: 10914760. DOI: 10.1038/s41467-024-46357-x.

Early Protective Role of Inflammation in Cardiac Remodeling and Heart Failure: Focus on TNFα and Resident Macrophages.

Besse S, Nadaud S, Balse E, Pavoine C Cells. 2022; 11(7).

PMID: 35406812 PMC: 8998130. DOI: 10.3390/cells11071249.

References

Revelo X, Parthiban P, Chen C, Barrow F, Fredrickson G, Wang H . Cardiac Resident Macrophages Prevent Fibrosis and Stimulate Angiogenesis. Circ Res. 2021; 129(12):1086-1101. PMC: 8638822. DOI: 10.1161/CIRCRESAHA.121.319737. View

Martini E, Kunderfranco P, Peano C, Carullo P, Cremonesi M, Schorn T . Single-Cell Sequencing of Mouse Heart Immune Infiltrate in Pressure Overload-Driven Heart Failure Reveals Extent of Immune Activation. Circulation. 2019; 140(25):2089-2107. DOI: 10.1161/CIRCULATIONAHA.119.041694. View

Hunter J, Chien K . Signaling pathways for cardiac hypertrophy and failure. N Engl J Med. 1999; 341(17):1276-83. DOI: 10.1056/NEJM199910213411706. View

Nevers T, Salvador A, Velazquez F, Ngwenyama N, Carrillo-Salinas F, Aronovitz M . Th1 effector T cells selectively orchestrate cardiac fibrosis in nonischemic heart failure. J Exp Med. 2017; 214(11):3311-3329. PMC: 5679176. DOI: 10.1084/jem.20161791. View

Adamo L, Rocha-Resende C, Prabhu S, Mann D . Reappraising the role of inflammation in heart failure. Nat Rev Cardiol. 2020; 17(5):269-285. DOI: 10.1038/s41569-019-0315-x. View

Bajpai G, Bredemeyer A, Li W, Zaitsev K, Koenig A, Lokshina I . Tissue Resident CCR2- and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury. Circ Res. 2018; 124(2):263-278. PMC: 6626616. DOI: 10.1161/CIRCRESAHA.118.314028. View

Lavine K, Epelman S, Uchida K, Weber K, Nichols C, Schilling J . Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart. Proc Natl Acad Sci U S A. 2014; 111(45):16029-34. PMC: 4234568. DOI: 10.1073/pnas.1406508111. View

Trenson S, Hermans H, Craps S, Pokreisz P, de Zeeuw P, Van Wauwe J . Cardiac Microvascular Endothelial Cells in Pressure Overload-Induced Heart Disease. Circ Heart Fail. 2021; 14(1):e006979. DOI: 10.1161/CIRCHEARTFAILURE.120.006979. View

Liao X, Shen Y, Zhang R, Sugi K, Vasudevan N, Alaiti M . Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy. Proc Natl Acad Sci U S A. 2018; 115(20):E4661-E4669. PMC: 5960298. DOI: 10.1073/pnas.1720065115. View

10.

Dick S, Zaman R, Epelman S . Using High-Dimensional Approaches to Probe Monocytes and Macrophages in Cardiovascular Disease. Front Immunol. 2019; 10:2146. PMC: 6751379. DOI: 10.3389/fimmu.2019.02146. View

11.

Nevers T, Salvador A, Grodecki-Pena A, Knapp A, Velazquez F, Aronovitz M . Left Ventricular T-Cell Recruitment Contributes to the Pathogenesis of Heart Failure. Circ Heart Fail. 2015; 8(4):776-87. PMC: 4512916. DOI: 10.1161/CIRCHEARTFAILURE.115.002225. View

12.

Dick S, Macklin J, Nejat S, Momen A, Clemente-Casares X, Althagafi M . Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction. Nat Immunol. 2018; 20(1):29-39. PMC: 6565365. DOI: 10.1038/s41590-018-0272-2. View

13.

Leuschner F, Dutta P, Gorbatov R, Novobrantseva T, Donahoe J, Courties G . Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat Biotechnol. 2011; 29(11):1005-10. PMC: 3212614. DOI: 10.1038/nbt.1989. View

14.

Patel B, Ismahil M, Hamid T, Bansal S, Prabhu S . Mononuclear Phagocytes Are Dispensable for Cardiac Remodeling in Established Pressure-Overload Heart Failure. PLoS One. 2017; 12(1):e0170781. PMC: 5268479. DOI: 10.1371/journal.pone.0170781. View

15.

Levy D, Garrison R, Savage D, Kannel W, CASTELLI W . Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med. 1990; 322(22):1561-6. DOI: 10.1056/NEJM199005313222203. View

16.

Hein S, Arnon E, Kostin S, Schonburg M, Elsasser A, Polyakova V . Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms. Circulation. 2003; 107(7):984-91. DOI: 10.1161/01.cir.0000051865.66123.b7. View

17.

Patel B, Bansal S, Ismahil M, Hamid T, Rokosh G, Mack M . CCR2 Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure Overload. JACC Basic Transl Sci. 2018; 3(2):230-244. PMC: 6059350. DOI: 10.1016/j.jacbts.2017.12.006. View

18.

Hamilton J, Cook A, Tak P . Anti-colony-stimulating factor therapies for inflammatory and autoimmune diseases. Nat Rev Drug Discov. 2016; 16(1):53-70. DOI: 10.1038/nrd.2016.231. View

19.

Epelman S, Lavine K, Beaudin A, Sojka D, Carrero J, Calderon B . Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity. 2014; 40(1):91-104. PMC: 3923301. DOI: 10.1016/j.immuni.2013.11.019. View

20.

Xia Y, Lee K, Li N, Corbett D, Mendoza L, Frangogiannis N . Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload. Histochem Cell Biol. 2008; 131(4):471-81. PMC: 2782393. DOI: 10.1007/s00418-008-0541-5. View