Therapeutic Potential of Marine Peptides in Cervical and Ovarian Cancers

Overview

Journal Mol Cell Biochem

Publisher Springer

Specialty Biochemistry

Date 2021 Dec 2

PMID 34855045

Citations 7

Authors

Salman Ahmed

Haroon Khan

Sajad Fakhri

Michael Aschner

Wai San Cheang

Affiliations

Soon will be listed here.

Abstract

Cervical and ovarian cancers contribute significantly to female morbidity and mortality worldwide. The current standard of treatment, including surgical removal, radiation therapy, and chemotherapy, offers poor outcomes. There are many side effects to traditional chemotherapeutic agents and treatment-resistant types, and often the immune response is depressed. As a result, traditional approaches have evolved to include new alternative remedies, such as natural compounds. Aquatic species provide a rich supply of possible drugs. The potential anti-cancer peptides are less toxic to normal cells and can attenuate multiple drug resistance by providing an efficacious treatment approach. The physiological effects of marine peptides are described in this review focusing on various pathways, such as apoptosis, microtubule balance disturbances, suppression of angiogenesis, cell migration/invasion, and cell viability. The review also highlights the potential role of marine peptides as safe and efficacious therapeutic agent for the treatment of cervical and ovarian cancers.

Citing Articles

Exploring the seas for cancer cures: the promise of marine-derived bioactive peptide.

Rafieezadeh D, Abbaspour M Int J Biochem Mol Biol. 2024; 15(4):100-106.

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Peptides for diagnosis and treatment of ovarian cancer.

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