Knowledge and Proportion of COVID-19 Vaccination and Associated Factors Among Cancer Patients Attending Public Hospitals of Addis Ababa, Ethiopia, 2021: A Multicenter Study

Overview

Journal Infect Drug Resist

Publisher Dove Medical Press

Date 2021 Dec 1

PMID 34848979

Citations 25

Authors

Fitalew Tadele Admasu

Affiliations

Soon will be listed here.

Abstract

Background: Cancer patients are classified as being at high risk of contracting COVID-19 infection, hospitalization, and death and were recommended to have early access to the limited COVID-19 vaccine. However, there are limited studies on the knowledge and acceptance of the COVID-19 vaccine among cancer patients. Therefore, this study aimed at assessing the awareness, readiness, and associated factors among cancer patients.

Methods: Institution-based cross-sectional study was conducted on 422 cancer patients from May to August, 2021. A structured interviewer-administered questionnaire was used to collect primary data. A systematic random sampling technique was used to select study participants. Descriptive statistics and binary logistic regression followed by multivariable analysis were performed to investigate the independent association of factors with the outcome variable. Finally, statistical significance was declared at P <0.05 using AOR and 95% CI.

Results: From the 422 cancer patients who participated, 77 (18.2%) had a history of COVID-19 infection, and 224 (55%) believe that the cancer disease will not make them more vulnerable to be infected by COVID-19. Accordingly, younger age (18-30 years) (AOR = 2.73: 95% CI: 0.18, 4.51), female (AOR = 6.4: 95% CI: 0.7, 13.8), having information about COVID-19 vaccine (AOR = 6.9: 95% CI: 3.1, 15.2), COVID-19 infection history (AOR = 6.0: 95% CI: 2.5, 11.8), duration since cancer diagnosis (≥10 years) (AOR= 6.2: 95% CI: 2.6, 14.7), and belief about the likelihood of dying of COVID-19 infection (AOR = 3.05: 95% CI: 1.03, 4.05) were the independent predictors of the likelihood of receiving COVID-19 vaccine among cancer patients.

Conclusion: This study has found significant cancer patients with poor knowledge about the vaccine, and the percentage of both the first and second round of COVID-19 vaccination was small. Therefore, information communication with cancer patients and oncologists about the COVID-19 vaccine may help to decrease vaccine hesitancy.

Citing Articles

Understanding the COVID-19 vaccine uptake, acceptance, and hesitancy in Ethiopia and Tanzania: a scoping review.

Gudina E, Muro F, Kyala N, Melaku T, Sorensen J, Meyrowitsch D Front Public Health. 2024; 12:1422673.

PMID: 39588164 PMC: 11586356. DOI: 10.3389/fpubh.2024.1422673.

The risk perception of COVID-19 and vaccine uptake among patients with chronic illnesses at a tertiary health facility in Nigeria.

Fasiku M, Aibinuomo O, Akande O, Kayode T, Aliu-Ayinde M, Adejoro I Ghana Med J. 2024; 58(3):198-206.

PMID: 39398092 PMC: 11465721. DOI: 10.4314/gmj.v58i3.4.

COVID-19 vaccine acceptance and its association with knowledge and attitude among patients with chronic diseases in Ethiopia.

Tsega T, Kebede A, Dessie T, Adane B, Yalew M, Ahmed A Hum Vaccin Immunother. 2024; 20(1):2350815.

PMID: 38757639 PMC: 11110712. DOI: 10.1080/21645515.2024.2350815.

Predictors of willingness to accept COVID-19 vaccine among adults.

Huka A, Alemeyehu L, Jara D, Ayele A, Shifa T Front Epidemiol. 2024; 3:1240557.

PMID: 38455924 PMC: 10911030. DOI: 10.3389/fepid.2023.1240557.

Cross-sectional survey evaluating the psychological impact of the COVID-19 vaccination campaign in patients with cancer: The VACCINATE study.

Tregnago D, Avancini A, Belluomini L, Trestini I, Sposito M, Insolda J PLoS One. 2024; 19(1):e0290792.

PMID: 38271378 PMC: 10810487. DOI: 10.1371/journal.pone.0290792.

References

Wang Q, Berger N, Xu R . When hematologic malignancies meet COVID-19 in the United States: Infections, death and disparities. Blood Rev. 2020; 47:100775. PMC: 7833659. DOI: 10.1016/j.blre.2020.100775. View

Brodziak A, Sigorski D, Osmola M, Wilk M, Gawlik-Urban A, Kiszka J . Attitudes of Patients with Cancer towards Vaccinations-Results of Online Survey with Special Focus on the Vaccination against COVID-19. Vaccines (Basel). 2021; 9(5). PMC: 8142983. DOI: 10.3390/vaccines9050411. View

Kwok K, Li K, Wei W, Tang A, Wong S, Lee S . Editor's Choice: Influenza vaccine uptake, COVID-19 vaccination intention and vaccine hesitancy among nurses: A survey. Int J Nurs Stud. 2020; 114:103854. PMC: 7831770. DOI: 10.1016/j.ijnurstu.2020.103854. View

Carreira H, Strongman H, Peppa M, McDonald H, Dos-Santos-Silva I, Stanway S . Prevalence of COVID-19-related risk factors and risk of severe influenza outcomes in cancer survivors: A matched cohort study using linked English electronic health records data. EClinicalMedicine. 2021; 29-30:100656. PMC: 7788436. DOI: 10.1016/j.eclinm.2020.100656. View

Rogado J, Obispo B, Pangua C, Serrano-Montero G, Martin Marino A, Perez-Perez M . Covid-19 transmission, outcome and associated risk factors in cancer patients at the first month of the pandemic in a Spanish hospital in Madrid. Clin Transl Oncol. 2020; 22(12):2364-2368. PMC: 7246222. DOI: 10.1007/s12094-020-02381-z. View

Barriere J, Gal J, Hoch B, Cassuto O, Leysalle A, Chamorey E . Acceptance of SARS-CoV-2 vaccination among French patients with cancer: a cross-sectional survey. Ann Oncol. 2021; 32(5):673-674. PMC: 7846886. DOI: 10.1016/j.annonc.2021.01.066. View

Moujaess E, Bou Zeid N, Samaha R, Sawan J, Kourie H, Labaki C . Perceptions of the COVID-19 vaccine among patients with cancer: a single-institution survey. Future Oncol. 2021; 17(31):4071-4079. PMC: 8328088. DOI: 10.2217/fon-2021-0265. View

Herrmann A, Hall A, Proietto A . Using the Health Belief Model to explore why women decide for or against the removal of their ovaries to reduce their risk of developing cancer. BMC Womens Health. 2018; 18(1):184. PMC: 6236993. DOI: 10.1186/s12905-018-0673-2. View

Fillmore N, La J, Szalat R, Tuck D, Nguyen V, Yildirim C . Prevalence and Outcome of COVID-19 Infection in Cancer Patients: A National Veterans Affairs Study. J Natl Cancer Inst. 2020; 113(6):691-698. PMC: 7665587. DOI: 10.1093/jnci/djaa159. View

10.

Belsti Y, Gela Y, Akalu Y, Dagnew B, Getnet M, Seid M . Willingness of Ethiopian Population to Receive COVID-19 Vaccine. J Multidiscip Healthc. 2021; 14:1233-1243. PMC: 8169050. DOI: 10.2147/JMDH.S312637. View

11.

Zewude B, Belachew A . Intention to Receive the Second Round of COVID-19 Vaccine Among Healthcare Workers in Eastern Ethiopia. Infect Drug Resist. 2021; 14:3071-3082. PMC: 8364848. DOI: 10.2147/IDR.S326055. View

12.

Villarreal-Garza C, Vaca-Cartagena B, Becerril-Gaitan A, Ferrigno A, Mesa-Chavez F, Platas A . Attitudes and Factors Associated With COVID-19 Vaccine Hesitancy Among Patients With Breast Cancer. JAMA Oncol. 2021; 7(8):1242-1244. PMC: 8193544. DOI: 10.1001/jamaoncol.2021.1962. View

13.

Zingg A, Siegrist M . Measuring people's knowledge about vaccination: developing a one-dimensional scale. Vaccine. 2012; 30(25):3771-7. DOI: 10.1016/j.vaccine.2012.03.014. View

14.

Dashraath P, Wong J, Lim M, Lim L, Li S, Biswas A . Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstet Gynecol. 2020; 222(6):521-531. PMC: 7270569. DOI: 10.1016/j.ajog.2020.03.021. View

15.

Richardson S, Hirsch J, Narasimhan M, Crawford J, McGinn T, Davidson K . Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 2020; 323(20):2052-2059. PMC: 7177629. DOI: 10.1001/jama.2020.6775. View

16.

Corti C, Crimini E, Tarantino P, Pravettoni G, Eggermont A, Delaloge S . SARS-CoV-2 vaccines for cancer patients: a call to action. Eur J Cancer. 2021; 148:316-327. PMC: 7904467. DOI: 10.1016/j.ejca.2021.01.046. View

17.

Chun J, Kim S, Park E, Park S, Koh S, Cha Y . Cancer Patients' Willingness to Take COVID-19 Vaccination: A Nationwide Multicenter Survey in Korea. Cancers (Basel). 2021; 13(15). PMC: 8345425. DOI: 10.3390/cancers13153883. View

18.

Wahed T, Kaukab S, Saha N, Khan I, Khanam F, Chowdhury F . Knowledge of, attitudes toward, and preventive practices relating to cholera and oral cholera vaccine among urban high-risk groups: findings of a cross-sectional study in Dhaka, Bangladesh. BMC Public Health. 2013; 13:242. PMC: 3608226. DOI: 10.1186/1471-2458-13-242. View

19.

Yu J, Ouyang W, Chua M, Xie C . SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China. JAMA Oncol. 2020; 6(7):1108-1110. PMC: 7097836. DOI: 10.1001/jamaoncol.2020.0980. View

20.

Goyal P, Choi J, Pinheiro L, Schenck E, Chen R, Jabri A . Clinical Characteristics of Covid-19 in New York City. N Engl J Med. 2020; 382(24):2372-2374. PMC: 7182018. DOI: 10.1056/NEJMc2010419. View