Mid-term Results of a New Femoral Prosthesis Using Ti-Nb-Sn Alloy with Low Young's Modulus

Overview

Journal BMC Musculoskelet Disord

Publisher Biomed Central

Specialties Orthopedics
Physiology

Date 2021 Nov 27

PMID 34836525

Citations 9

Authors

Daisuke Chiba

Norikazu Yamada

Yu Mori

Masamizu Oyama

Susumu Ohtsu

Yoshiyuki Kuwahara

Kazuyoshi Baba

Hidetatsu Tanaka

Toshimi Aizawa

Shuji Hanada

Eiji Itoi

Affiliations

Soon will be listed here.

Abstract

Background: This study was performed to investigate the mid-term results of Ti-Nb-Sn (TNS) alloy stem with a low Young's modulus.

Methods: This study was a multicenter prospective cohort study. A total of 40 primary total hip arthroplasties performed between April 2016 and September 2017 was enrolled in this study. With the unique functional gradient properties by heating treatment, the strength of the proximal portion was enhanced, while the distal portion maintained a low Young's modulus. The surgeries were performed through the posterolateral approach using the TNS alloy stems. Radiographs were taken from immediately after surgeries until 3 years, and stress shielding and subsidence of the stems were evaluated. The incidences of the stem breakage were also assessed. Clinical assessments were performed using Japanese Orthopaedic Association (JOA) and Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JHEQ) scores.

Results: Among the 40 enrolled patients, 36 patients were female and 4 were male. At 3 years after surgery, there were no radiologic signs of loosening, subsidence, or breakage of the stem. Stress shielding was observed in 26 hips (65%). Of 26 hips, 16 hips (40%) were grade 1 and 10 hips (25%) were grade 2. There was no advanced stress shielding. The JOA and JHEQ scores significantly improved compared with the preoperative scores.

Conclusion: The current study using a new TNS alloy femoral stem showed good clinical outcomes at 3-year follow-up. Radiologically, there was no loosening or subsidence of the stem. The mild stress shielding was observed in 65% of patients.

Trial Registration: Current Controlled Trials ISRCTN21241251 . The date of registration was October 26, 2021. Retrospectively registered.

Citing Articles

Preoperative Osteoporosis Treatment Reduces Stress Shielding in Total Hip Arthroplasty.

Kanabuchi R, Mori Y, Baba K, Tanaka H, Kuriyama Y, Fukuchi H Med Sci (Basel). 2025; 13(1).

PMID: 39982235 PMC: 11843854. DOI: 10.3390/medsci13010010.

Debulking of the Femoral Stem in a Primary Total Hip Joint Replacement: A Novel Method to Reduce Stress Shielding.

Sunavala-Dossabhoy G, Saba B, McCarthy K Bioengineering (Basel). 2024; 11(4).

PMID: 38671814 PMC: 11047840. DOI: 10.3390/bioengineering11040393.

TiNbSn stems with gradient changes of Young's modulus and stiffness reduce stress shielding compared to the standard fit-and-fill stems.

Baba K, Mori Y, Chiba D, Kuwahara Y, Kurishima H, Tanaka H Eur J Med Res. 2023; 28(1):214.

PMID: 37400903 PMC: 10316607. DOI: 10.1186/s40001-023-01199-z.

Recent Methods for Modifying Mechanical Properties of Tissue-Engineered Scaffolds for Clinical Applications.

Johnston A, Callanan A Biomimetics (Basel). 2023; 8(2).

PMID: 37218791 PMC: 10204517. DOI: 10.3390/biomimetics8020205.

Approaches to reduce periprosthetic bone resorption after total hip arthroplasty.

Mori Y, Mori N J Bone Miner Metab. 2023; 41(4):575-576.

PMID: 37029833 DOI: 10.1007/s00774-023-01423-0.

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