The Role of the Gluten-Free Diet in the Management of Seronegative Enteropathy
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The differential diagnosis and treatment of seronegative enteropathy, also termed seronegative villous atrophy (SNVA), is a clinical challenge. Although seronegative coeliac disease (CD) is a frequent cause of SNVA, the aetiology can include immune-mediated, inflammatory, infectious, and drug-related forms. As a misdiagnosis of SNVA can result in patients being unnecessarily placed on a lifelong strict gluten-free diet or even given incorrect immunosuppressive therapy, the aim of this paper is to provide an evidence-based and practical approach for the workup and management of SNVA.
The Gluten-Free Diet for Celiac Disease: Critical Insights to Better Understand Clinical Outcomes.
Simon E, Molero-Luis M, Fueyo-Diaz R, Costas-Batlle C, Crespo-Escobar P, Montoro-Huguet M Nutrients. 2023; 15(18).
PMID: 37764795 PMC: 10537989. DOI: 10.3390/nu15184013.