» Articles » PMID: 34831657

Reduction in Blood Lead Concentration in Children Across the Republic of Georgia Following Interventions to Address Widespread Exceedance of Reference Value in 2019

Overview
Publisher MDPI
Date 2021 Nov 27
PMID 34831657
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

In recent years, reports of lead contamination have dramatically increased in Georgia. Given concerns about the exposure of children to lead (Pb), the National Multiple Indicator Cluster Survey (MICS-2018) included a blood sampling component. The results showed that 41% of the children that participated had blood Pb levels (BLL) ≥ 5 µg/dL and that BLL in children living in Western Georgia were higher than those in Eastern regions. In response to these findings, NCDC implemented written and verbal advice to the families of children who participated in the MICS-2018 on how to reduce Pb exposure. From August 2019 onwards, the state program of clinical follow-up was implemented. The design of this study was a longitudinal study. The intervention of interest was the public health advice and medical follow-up, and the outcome was defined as the difference in BLL between the MICS-2018 survey and the state program follow-up. We observed a significant overall reduction in median BLL between MICS-2018 and state program follow-up in both August 2019 and the latest results (until December 2019). However, we did not observe any significant further reduction between August and the most recent BLL results. In the Georgian setting, written and verbal communication targeting individual households, alongside home visits to the most exposed, effectively reduced BLL in children.

Citing Articles

A new environmental public health practice to manage current and future global health challenges through education, training, and capacity building.

Leonardi G, Zeka A, Ashworth M, Bouland C, Crabbe H, Duarte-Davidson R Front Public Health. 2024; 12:1373490.

PMID: 39655257 PMC: 11627177. DOI: 10.3389/fpubh.2024.1373490.


Identifying Sources of Lead Exposure for Children in the Republic of Georgia, with Lead Isotope Ratios.

Leonardi G, Ruadze E, Saei A, Laycock A, Chenery S, Crabbe H Int J Environ Res Public Health. 2023; 20(20).

PMID: 37887650 PMC: 10606333. DOI: 10.3390/ijerph20206912.


The Use of Pb Isotope Ratios to Determine Environmental Sources of High Blood Pb Concentrations in Children: A Feasibility Study in Georgia.

Laycock A, Chenery S, Marchant E, Crabbe H, Saei A, Ruadze E Int J Environ Res Public Health. 2022; 19(22).

PMID: 36429725 PMC: 9690981. DOI: 10.3390/ijerph192215007.

References
1.
Can S, Bagci C, Ozaslan M, Bozkurt A, Cengiz B, Cakmak E . Occupational lead exposure effect on liver functions and biochemical parameters. Acta Physiol Hung. 2008; 95(4):395-403. DOI: 10.1556/APhysiol.95.2008.4.6. View

2.
Harari F, Sallsten G, Christensson A, Petkovic M, Hedblad B, Forsgard N . Blood Lead Levels and Decreased Kidney Function in a Population-Based Cohort. Am J Kidney Dis. 2018; 72(3):381-389. DOI: 10.1053/j.ajkd.2018.02.358. View

3.
Obeng-Gyasi E, Ferguson A, Stamatakis K, Province M . Combined Effect of Lead Exposure and Allostatic Load on Cardiovascular Disease Mortality-A Preliminary Study. Int J Environ Res Public Health. 2021; 18(13). PMC: 8297236. DOI: 10.3390/ijerph18136879. View

4.
Hilts S, Bock S, Oke T, Yates C, Copes R . Effect of interventions on children's blood lead levels. Environ Health Perspect. 1998; 106(2):79-83. PMC: 1533008. DOI: 10.1289/ehp.9810679. View

5.
Wheeler D, Boyle J, Raman S, Nelson E . Modeling elevated blood lead level risk across the United States. Sci Total Environ. 2021; 769:145237. DOI: 10.1016/j.scitotenv.2021.145237. View