Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments

Overview

Journal Front Bioeng Biotechnol

Date 2021 Nov 25

PMID 34820359

Citations 8

Authors

Lilan Cao

Huiying Su

Mengying Si

Jing Xu

Xin Chang

Jiajia Lv

Yuankun Zhai

Affiliations

Soon will be listed here.

Abstract

Tissue engineering is an emerging discipline that combines engineering and life sciences. It can construct functional biological structures or to replace native tissues or organs and minimize serious shortages of donor organs during tissue and organ reconstruction or transplantation. Organ transplantation has achieved success by using the tissue-engineered heart, liver, kidney, and other artificial organs, and the emergence of tissue-engineered bone also provides a new approach for the healing of human bone defects. In recent years, tissue engineering technology has gradually become an important technical method for dentistry research, and its application in stomatology-related research has also obtained impressive achievements. The purpose of this review is to summarize the research advances of tissue engineering and its application in stomatology. These aspects include tooth, periodontal, dental implant, cleft palate, oral and maxillofacial skin or mucosa, and oral and maxillofacial bone tissue engineering. In addition, this article also summarizes the commonly used cells, scaffolds, and growth factors in stomatology and discusses the limitations of tissue engineering in stomatology from the perspective of cells, scaffolds, and clinical applications.

Citing Articles

Investigating the Influence of a Tooth Absence on Facial Bone Growth Using a Porcine Model.

Szkopek D, Wychowanski P, Zaworski K, Seklecka B, Starzynski R, Lipinski P Int J Mol Sci. 2024; 25(23).

PMID: 39684221 PMC: 11640821. DOI: 10.3390/ijms252312509.

Exosome-Laden Hydrogels as Promising Carriers for Oral and Bone Tissue Engineering: Insight into Cell-Free Drug Delivery.

Villani C, Murugan P, George A Int J Mol Sci. 2024; 25(20).

PMID: 39456873 PMC: 11508290. DOI: 10.3390/ijms252011092.

Correlation between tooth decay and insulin resistance in normal weight males prompts a role for myo-inositol as a regenerative factor in dentistry and oral surgery: a feasibility study.

Barbaro F, Di Conza G, Quartulli F, Quarantini E, Quarantini M, Zini N Front Bioeng Biotechnol. 2024; 12:1374135.

PMID: 39144484 PMC: 11321979. DOI: 10.3389/fbioe.2024.1374135.

Recent trends and perspectives in reconstruction and regeneration of intra/extra-oral wounds using tissue-engineered oral mucosa equivalents.

Izumi K, Yortchan W, Aizawa Y, Kobayashi R, Hoshikawa E, Ling Y Jpn Dent Sci Rev. 2023; 59:365-374.

PMID: 37954029 PMC: 10632115. DOI: 10.1016/j.jdsr.2023.10.002.

Ligaplants: Uprising Regimen in the Glebe of Implant Dentistry.

Bajaj P, Shirbhate U, Dare S Cureus. 2023; 15(9):e45968.

PMID: 37900437 PMC: 10600504. DOI: 10.7759/cureus.45968.

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