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Comparison of Chronic Widespread Pain Prevalence with Different Criteria in Two Cohorts of Rheumatoid Arthritis

Overview
Journal Clin Rheumatol
Publisher Springer
Specialty Rheumatology
Date 2021 Nov 23
PMID 34812975
Citations 1
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Abstract

Objective: This study aims to investigate chronic widespread pain with the 1990 (CWP1990) and 2019 (CWP2019) definitions 6 years after the onset of rheumatoid arthritis (RA), in one patient cohort with tight controls and one conventional cohort, and factors associated with reporting CWP1990 and CWP2019, respectively.

Methods: A cohort of 80 RA patients with monthly visits to the physician the first 6 months was compared to a cohort of 101 patients from the same clinic with conventional follow-up. Both cohorts had early RA (< 13 months). The prevalence of CWP1990 and the more stringent CWP2019 were in a 6-year follow-up investigated with a questionnaire, including a pain mannequin and a fear-avoidance beliefs questionnaire.

Results: In the tight control cohort, 10% reported CWP2019 after 6 years compared to 23% in the conventional cohort (p = 0.026). There was no difference when using the CWP1990 definition (27% vs 31%, p = 0.546). When adjusted for important baseline data, the odds ratio for having CWP2019 was 2.57 (95% CI 1.02-6.50), in the conventional group compared to the tight control group (p = 0.046). A high level of fear-avoidance behaviour towards physical activity was associated with CWP2019, OR 10.66 (95% CI 1.01-112.14), but not with CWP1990 in the tight control cohort.

Conclusion: A more stringent definition of CWP identifies patients with a more serious pain condition, which potentially could be prevented by an initial tight control management. Besides tight control, caregivers should pay attention to fear-avoidance behaviour and tailor treatment.

Key Points: • CWP2019 is a more stringent definition of chronic widespread pain and identifies patients with a more serious pain condition. • Patients with a serious pain condition could be helped by frequent follow-ups. • This study suggests that a special attention of fear-avoidance behaviour towards physical activity in patients with RA is needed.

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References
1.
Wolfe F, Butler S, Fitzcharles M, Hauser W, Katz R, Mease P . Revised chronic widespread pain criteria: development from and integration with fibromyalgia criteria. Scand J Pain. 2019; 20(1):77-86. DOI: 10.1515/sjpain-2019-0054. View

2.
Wolfe F, Hauser W, Hassett A, Katz R, Walitt B . The development of fibromyalgia--I: examination of rates and predictors in patients with rheumatoid arthritis (RA). Pain. 2010; 152(2):291-299. DOI: 10.1016/j.pain.2010.09.027. View

3.
Pardo F, Bondesson E, Schelin M, Joud A . A diagnosis of rheumatoid arthritis, endometriosis or IBD is associated with later onset of fibromyalgia and chronic widespread pain. Eur J Pain. 2019; 23(8):1563-1573. DOI: 10.1002/ejp.1432. View

4.
Heinricher M, Tavares I, Leith J, Lumb B . Descending control of nociception: Specificity, recruitment and plasticity. Brain Res Rev. 2009; 60(1):214-25. PMC: 2894733. DOI: 10.1016/j.brainresrev.2008.12.009. View

5.
Demmelmaier I, Bergman P, Nordgren B, Jensen I, Opava C . Current and maintained health-enhancing physical activity in rheumatoid arthritis: a cross-sectional study. Arthritis Care Res (Hoboken). 2013; 65(7):1166-76. DOI: 10.1002/acr.21951. View