Reassortant Influenza A(H1N1)pdm09 Virus in Elderly Woman, Denmark, January 2021

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2021 Nov 22

PMID 34808097

Citations 2

Authors

Jakob N Nissen

Sophie J George

Charlotte K Hjulsager

Jesper S Krog

Xiaohui C Nielsen

Tina V Madsen

Klara M Andersen

Tyra G Krause

Lasse S Vestergaard

Lars E Larsen

Ramona Trebbien

Affiliations

Soon will be listed here.

Abstract

A case of human infection with influenza A(H1N1)pdm09 virus containing a nonstructural gene highly similar to Eurasian avian-like H1Nx swine influenza virus was detected in Denmark in January 2021. We describe the clinical case and report testing results of the genetic and antigenic characterizations of the virus.

Citing Articles

Rapid surge of reassortant A(H1N1) influenza viruses in Danish swine and their zoonotic potential.

Ryt-Hansen P, George S, Hjulsager C, Trebbien R, Krog J, Ciucani M Emerg Microbes Infect. 2025; 14(1):2466686.

PMID: 39945729 PMC: 11849018. DOI: 10.1080/22221751.2025.2466686.

Experimental infection of pigs and ferrets with "pre-pandemic," human-adapted, and swine-adapted variants of the H1N1pdm09 influenza A virus reveals significant differences in viral dynamics and pathological manifestations.

Kristensen C, Laybourn H, Crumpton J, Martiny K, Webb A, Ryt-Hansen P PLoS Pathog. 2023; 19(12):e1011838.

PMID: 38048355 PMC: 10721187. DOI: 10.1371/journal.ppat.1011838.

Severe Human Case of Zoonotic Infection with Swine-Origin Influenza A Virus, Denmark, 2021.

Andersen K, Vestergaard L, Nissen J, George S, Ryt-Hansen P, Hjulsager C Emerg Infect Dis. 2022; 28(12):2561-2564.

PMID: 36418004 PMC: 9707568. DOI: 10.3201/eid2812.220935.

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