Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies

Overview

Journal Int J Bioprint

Specialty Biomedical Engineering

Date 2021 Nov 22

PMID 34805593

Citations 3

Authors

Abdulelah A Alrashoudi

Hamed I Albalawi

Ali H Aldoukhi

Manola Moretti

Panayiotis Bilalis

Malak Abedalthagafi

Charlotte A E Hauser

Affiliations

Soon will be listed here.

Abstract

The development of lateral flow immunoassay (LFIA) using three-dimensional (3D) printing and bioprinting technologies can enhance and accelerate the optimization process of the fabrication. Therefore, the main goal of this study is to investigate methods to speed up the developing process of a LFIA as a tool for community screening. To achieve this goal, an in-house developed robotic arm and microfluidic pumps were used to print the proteins during the development of the test. 3D printing technologies were used to design and print the housing unit for the testing strip. The proposed design was made by taking into consideration the environmental impact of this disposable medical device.

Citing Articles

Fusing Peptide Epitopes for Advanced Multiplex Serological Testing for SARS-CoV-2 Antibody Detection.

Aldoukhi A, Bilalis P, Alhattab D, Valle-Perez A, Susapto H, Perez-Pedroza R ACS Bio Med Chem Au. 2024; 4(1):37-52.

PMID: 38404747 PMC: 10885102. DOI: 10.1021/acsbiomedchemau.3c00010.

Micropillar enhanced FRET-CRISPR biosensor for nucleic acid detection.

Bao M, Dollery S, Yuqing F, Tobin G, Du K Lab Chip. 2023; 24(1):47-55.

PMID: 38019145 PMC: 11221459. DOI: 10.1039/d3lc00780d.

Proof-of-concept for speedy development of rapid and simple at-home method for potential diagnosis of early COVID-19 mutant infections using nanogold and aptamer.

Ellipilli S, Wang H, Lee W, Shu D, Guo P Nanomedicine. 2022; 45:102590.

PMID: 35905841 PMC: 9315840. DOI: 10.1016/j.nano.2022.102590.

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