Current and Future Uses of Continuous EEG in the NICU
Overview
Affiliations
Continuous EEG (cEEG) is a fundamental neurodiagnostic tool in the care of critically ill neonates and is increasingly recommended. cEEG enhances prognostication assessment of the background brain activity, plays a role in predicting which neonates are at risk for seizures when combined with clinical factors, and allows for accurate diagnosis and management of neonatal seizures. Continuous EEG is the gold standard method for diagnosis of neonatal seizures and should be used for detection of seizures in high-risk clinical conditions, differential diagnosis of paroxysmal events, and assessment of response to treatment. High costs associated with cEEG are a limiting factor in its widespread implementation. Centralized remote cEEG interpretation, automated seizure detection, and pre-natal EEG are potential future applications of this neurodiagnostic tool.
Amplitude-Integrated Electroencephalography: A Readily Available Tool for Neonatologists.
Lucena M, Balasundaram P, Hsu S, Silveira D, Rosen O Cureus. 2024; 16(8):e67018.
PMID: 39280460 PMC: 11402466. DOI: 10.7759/cureus.67018.
Rogers C, Meller S, Meyerhoff N, Volk H Front Vet Sci. 2024; 11:1419792.
PMID: 39071780 PMC: 11272624. DOI: 10.3389/fvets.2024.1419792.
Krishnan V, Ujjanappa V, Vegda H, Annayappa M, Wali P, Fattepur S Lancet Reg Health Southeast Asia. 2024; 25:100371.
PMID: 39021480 PMC: 467079. DOI: 10.1016/j.lansea.2024.100371.
Andrade-Machado R, Abushanab E, Patel N, Singh A World J Pediatr. 2024; 20(8):764-773.
PMID: 38997604 DOI: 10.1007/s12519-024-00816-z.
Acute seizure activity in neonatal inflammation-sensitized hypoxia-ischemia in mice.
June A, Matysik W, Marlicz M, Zucker E, Wagley P, Kuan C PLoS One. 2024; 19(1):e0295860.
PMID: 38206902 PMC: 10783742. DOI: 10.1371/journal.pone.0295860.