Paraneoplastic Myopathy in Pancreatic Cancer: a Case Report and Literature Review

Overview

Journal J Community Hosp Intern Med Perspect

Date 2021 Nov 22

PMID 34804404

Citations 2

Authors

Jessica Joanne Padniewski

Elizabeth Nelson

Istiaq Mian

Andrew Laczniak

Samuel Ives

Rawad Nasr

Affiliations

Soon will be listed here.

Abstract

Dermatomyositis (DM) and polymyositis (PM) are both immune-mediated inflammatory myopathies known to occur in paraneoplastic syndromes associated with a new diagnosis of malignancy, most commonly breast, ovarian, lung, pancreatic, stomach, colorectal, and Non-Hodgkin's lymphoma in DM and breast, lung, bladder cancer, and Non-Hodgkin's lymphoma in PM. While inflammatory markers such as creatine kinase (CK) may be elevated with either DM or PM, marked elevation is rare. Herein, we report a case of newly diagnosed pancreatic cancer presenting with inflammatory myopathy and marked CK elevation. We review the frequency of PM as a paraneoplastic syndrome, the association with marked CK elevation, and the association with pancreatic cancer.

Citing Articles

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