Mechanisms of COVID-19-induced Kidney Injury and Current Pharmacotherapies

Overview

Journal Inflamm Res

Specialties Allergy & Immunology
Pathology

Date 2021 Nov 21

PMID 34802072

Citations 19

Authors

Wissam H Faour

Ali Choaib

Elio Issa

Francesca El Choueiry

Khodor Shbaklo

Maryline Alhajj

Ramy Touma Sawaya

Zeina Harhous

Eman Alefishat

Moni Nader

Affiliations

Soon will be listed here.

Abstract

The COVID-19 pandemic created a worldwide debilitating health crisis with the entire humanity suffering from the deleterious effects associated with the high infectivity and mortality rates. While significant evidence is currently available online and targets various aspects of the disease, both inflammatory and noninflammatory kidney manifestations secondary to COVID-19 infection are still largely underrepresented. In this review, we summarized current knowledge about COVID-19-related kidney manifestations, their pathologic mechanisms as well as various pharmacotherapies used to treat patients with COVID-19. We also shed light on the effect of these medications on kidney functions that can further enhance renal damage secondary to the illness.

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