» Articles » PMID: 34791909

Correlation of Heart Rate Recovery and Heart Rate Variability with Atrial Fibrillation Progression

Overview
Journal J Int Med Res
Publisher Sage Publications
Specialty General Medicine
Date 2021 Nov 18
PMID 34791909
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: To examine the combination of heart rate recovery (HRR) and heart rate variability (HRV) in predicting atrial fibrillation (AF) progression.

Methods: Data from patients with a first detected episode of AF who underwent treadmill exercise testing and 24-h Holter electrocardiography were retrospectively analysed. Autonomic dysfunction was verified using HRR values. Sympathetic and parasympathetic modulation was analysed by HRV. AF progression was defined as transition from the first detected paroxysmal episode to persistent/permanent AF.

Results: Of 306 patients, mean LF/HF ratio and HRR did not differ significantly by AF progression regardless of age (< or ≥65 years). However, when the LF/HF ratio was divided into tertiles, in patients aged <65 years, the mid LF/HF (1.60-2.40) ratio was significantly associated with lower AF progression rates and longer maintenance of normal sinus rhythm. For patients aged <65 years, less metabolic equivalents were related to higher AF progression rates. For patients aged ≥65 years, a low HRR was associated with high AF progression rates.

Conclusion: In relatively younger age, high physical capacity and balanced autonomic nervous system regulation are important predictors of AF progression. Evaluation of autonomic function assessed by age could predict AF progression.

Citing Articles

Delayed blood pressure recovery after exercise stress test is associated with autonomic dysfunction and pulse pressure in a middle-aged healthy group.

Lee H, Kim H, Oh S, Park J, Jang J, Chun K PLoS One. 2023; 18(10):e0285961.

PMID: 37788242 PMC: 10547162. DOI: 10.1371/journal.pone.0285961.

References
1.
Molina L, Mont L, Marrugat J, Berruezo A, Brugada J, Bruguera J . Long-term endurance sport practice increases the incidence of lone atrial fibrillation in men: a follow-up study. Europace. 2008; 10(5):618-23. DOI: 10.1093/europace/eun071. View

2.
Everett B, Conen D, Buring J, Moorthy M, Lee I, Albert C . Physical activity and the risk of incident atrial fibrillation in women. Circ Cardiovasc Qual Outcomes. 2011; 4(3):321-7. PMC: 3097307. DOI: 10.1161/CIRCOUTCOMES.110.951442. View

3.
Camm A, Breithardt G, Crijns H, Dorian P, Kowey P, Le Heuzey J . Real-life observations of clinical outcomes with rhythm- and rate-control therapies for atrial fibrillation RECORDAF (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation). J Am Coll Cardiol. 2011; 58(5):493-501. DOI: 10.1016/j.jacc.2011.03.034. View

4.
de Vos C, Pisters R, Nieuwlaat R, Prins M, Tieleman R, Coelen R . Progression from paroxysmal to persistent atrial fibrillation clinical correlates and prognosis. J Am Coll Cardiol. 2010; 55(8):725-31. DOI: 10.1016/j.jacc.2009.11.040. View

5.
Zhang Y, Qiu C, Davis P, Jhaveri M, Prystowsky E, Kowey P . Predictors of progression of recently diagnosed atrial fibrillation in REgistry on Cardiac Rhythm DisORDers Assessing the Control of Atrial Fibrillation (RecordAF)-United States cohort. Am J Cardiol. 2013; 112(1):79-84. DOI: 10.1016/j.amjcard.2013.02.056. View