Gold Standard for Diagnosis of DPN

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2021 Nov 12

PMID 34764937

Citations 42

Authors

Yongchun Yu

Affiliations

Soon will be listed here.

Abstract

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus. It often causes symmetrical paresthesia, loss of sensation, and hyperalgesia. Without early intervention, it might lead to diabetic foot ulceration, gangrene, and subsequent amputation in people with diabetes. DPN is an insidious disease and often underdiagnosed. This paper reviews the current national and international prevalence of DPN, screening methods for early DPN, including quantitative sensory measurement, neurological function scoring system, confocal microscopy, and high-frequency ultrasound, and summarizes the related research progress, clinical application, and development prospects of these methods in recent years.

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