BETter Insight into PRC2-mutated T-ALL
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
References
1.
Kim J, Lee Y, Lu X, Song B, Fong K, Cao Q
. Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator. Cell Rep. 2018; 25(10):2808-2820.e4.
PMC: 6342284.
DOI: 10.1016/j.celrep.2018.11.035.
View
2.
Gilan O, Rioja I, Knezevic K, Bell M, Yeung M, Harker N
. Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation. Science. 2020; 368(6489):387-394.
PMC: 7610820.
DOI: 10.1126/science.aaz8455.
View
3.
de Bock C, Demeyer S, Degryse S, Verbeke D, Sweron B, Gielen O
. HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development. Cancer Discov. 2018; 8(5):616-631.
DOI: 10.1158/2159-8290.CD-17-0583.
View
4.
Andrieu G, Kohn M, Simonin M, Smith C, Cieslak A, Dourthe M
. PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL. Blood. 2021; 138(19):1855-1869.
PMC: 9642784.
DOI: 10.1182/blood.2020010081.
View
5.
Laugesen A, Helin K
. Chromatin repressive complexes in stem cells, development, and cancer. Cell Stem Cell. 2014; 14(6):735-51.
DOI: 10.1016/j.stem.2014.05.006.
View