Roles of Calcitonin Gene-related Peptide in the Skin, and Other Physiological and Pathophysiological Functions

Overview

Journal Brain Behav Immun Health

Date 2021 Nov 8

PMID 34746878

Citations 26

Authors

Yee Jung Kim

Richard D Granstein

Affiliations

Soon will be listed here.

Abstract

Skin immunity is regulated by many mediator molecules. One is the neuropeptide calcitonin gene-related peptide (CGRP). CGRP has roles in regulating the function of components of the immune system including T cells, B cells, dendritic cells (DCs), endothelial cells (ECs), and mast cells (MCs). Herein we discuss actions of CGRP in mediating inflammatory and vascular effects in various cutaneous models and disorders.

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