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Posterior Reversible Encephalopathy Syndrome: A Rare Complication in COVID-19

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Journal Cureus
Date 2021 Nov 4
PMID 34733597
Citations 1
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Abstract

The coronavirus disease 2019 (COVID-19) has a broad spectrum of manifestations. Neurological complications are not uncommon in patients with COVID-19. We report the case of a middle-aged man who presented with a cough and fever. He had a decreased oxygen saturation and required supplementary oxygen therapy. During his stay, he developed an unexplained seizure. Computed tomography of the brain revealed vasogenic edema located posteriorly. Subsequently, magnetic resonance imaging demonstrated subcortical white-matter hyperdensities, in keeping with the diagnosis of posterior reversible encephalopathy syndrome, an exceedingly rare manifestation in COVID-19. This condition should be kept in mind when encountering unexplained neurological manifestations that developed in patients with COVID-19.

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Posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome in patients with COVID-19 infection: is there a link? A systematic review and case report analysis.

Bonura A, Iaccarino G, Rossi S, Capone F, Motolese F, Calandrelli R J Neurol. 2023; 270(6):2826-2852.

PMID: 37014421 PMC: 10071475. DOI: 10.1007/s00415-023-11684-4.

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