Nanodiagnostics to Face SARS-CoV-2 and Future Pandemics: From an Idea to the Market and Beyond

Overview

Journal ACS Nano

Publisher American Chemical Society

Specialty Biotechnology

Date 2021 Oct 27

PMID 34705433

Citations 12

Authors

Giulio Rosati

Andrea Idili

Claudio Parolo

Celia Fuentes-Chust

Enric Calucho

Liming Hu

Cecilia de Carvalho Castro E Silva

Lourdes Rivas

Emily P Nguyen

Jose F Bergua

Ruslan Alvarez-Diduk

Jose Munoz

Christophe Junot

Oriol Penon

Dominique Monferrer

Emmanuel Delamarche

Arben Merkoci

Affiliations

Soon will be listed here.

Abstract

The COVID-19 pandemic made clear how our society requires quickly available tools to address emerging healthcare issues. Diagnostic assays and devices are used every day to screen for COVID-19 positive patients, with the aim to decide the appropriate treatment and containment measures. In this context, we would have expected to see the use of the most recent diagnostic technologies worldwide, including the advanced ones such as nano-biosensors capable to provide faster, more sensitive, cheaper, and high-throughput results than the standard polymerase chain reaction and lateral flow assays. Here we discuss why that has not been the case and why all the exciting diagnostic strategies published on a daily basis in peer-reviewed journals are not yet successful in reaching the market and being implemented in the clinical practice.

Citing Articles

Ultrasensitive Lateral Flow Immunoassay of Fluoroquinolone Antibiotic Gatifloxacin Using Au@Ag Nanoparticles as a Signal-Enhancing Label.

Hendrickson O, Byzova N, Panferov V, Zvereva E, Xing S, Zherdev A Biosensors (Basel). 2024; 14(12).

PMID: 39727863 PMC: 11674194. DOI: 10.3390/bios14120598.

Nanomaterial and interface advances in immunoassay biosensors.

Mata Calidonio J, Gomez-Marquez J, Hamad-Schifferli K J Phys Chem C Nanomater Interfaces. 2024; 126(42):17804-17815.

PMID: 38957865 PMC: 11218816. DOI: 10.1021/acs.jpcc.2c05008.

Rationally Designed DNA-Based Scaffolds and Switching Probes for Protein Sensing.

Chamorro A, Rossetti M, Bagheri N, Porchetta A Adv Biochem Eng Biotechnol. 2024; 187:71-106.

PMID: 38273204 DOI: 10.1007/10_2023_235.

Single-Response Duplexing of Electrochemical Label-Free Biosensor from the Same Tag.

Costa J, Pimentel G, Poker J, Merces L, Paschoalino W, Vieira L Adv Healthc Mater. 2024; 13(11):e2303509.

PMID: 38245830 PMC: 11468374. DOI: 10.1002/adhm.202303509.

Advances in nanobiosensors during the COVID-19 pandemic and future perspectives for the post-COVID era.

Kim Y, Min J Nano Converg. 2024; 11(1):3.

PMID: 38206526 PMC: 10784265. DOI: 10.1186/s40580-023-00410-5.

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