Diverse Vaccine Platforms Safeguarding Against SARS-CoV-2 and Its Variants
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Introduction: Appearances of SARS-CoV-2 variants have created havoc and additional challenges for the ongoing vaccination drive against pandemic COVID-19. Interestingly, several vaccine platforms are showing great potential to produce successful vaccines against SARS-CoV-2 and its variants. Billions of COVID-19 vaccine doses have been administered worldwide. Mix-and-Match COVID-19 vaccines involving the mixing of the same platform vaccines and also two different vaccine platforms may provide greater protection against SARS-CoV-2 and its variants. COVID-19 vaccines have become one of the most important tools to mitigate the ongoing pandemic COVID-19.
Areas Covered: We describe SARS-Cov-2 variants, their impact on the population, COVID-19 vaccines, diverse vaccine platforms, doses of vaccines, the efficacy of vaccines against SARS-CoV-2 and its variants, mitigation of the COVID-19 transmission- alternatives to vaccines.
Expert Opinion: Diverse vaccine platforms may safeguard against ongoing, deadly SARS-CoV-2 and its infectious variants. The efficacies of COVID-19 vaccines are significantly high after the administration of the second dose. Further, it protects individuals including vulnerable patients with co-morbidities from SARS-CoV-2 and its variants. The hospitalizations and deaths of the individuals may be prevented by COVID-19 vaccines.
Cui L, Li T, Lan M, Zhou M, Xue W, Zhang S iScience. 2024; 27(7):110208.
PMID: 39015149 PMC: 11251093. DOI: 10.1016/j.isci.2024.110208.
Sv P, Lorenz J, Ittamalla R, Dhama K, Chakraborty C, Kumar D Vaccines (Basel). 2022; 10(11).
PMID: 36423024 PMC: 9692646. DOI: 10.3390/vaccines10111929.
Research progress of biosensors for detection of SARS-CoV-2 variants based on ACE2.
Wei H, Zhang C, Du X, Zhang Z Talanta. 2022; 251:123813.
PMID: 35952504 PMC: 9356646. DOI: 10.1016/j.talanta.2022.123813.