The Centrosome

Overview

Journal Cells

Publisher MDPI

Specialties Biochemistry
Biophysics
Cell Biology
Molecular Biology

Date 2021 Oct 23

PMID 34685637

Citations 6

Authors

Ralph Graf

Marianne Grafe

Irene Meyer

Kristina Mitic

Valentin Pitzen

Affiliations

Soon will be listed here.

Abstract

The centrosome of amoebae contains no centrioles and consists of a cylindrical layered core structure surrounded by a corona harboring microtubule-nucleating γ-tubulin complexes. It is the major centrosomal model beyond animals and yeasts. Proteomics, protein interaction studies by BioID and superresolution microscopy methods led to considerable progress in our understanding of the composition, structure and function of this centrosome type. We discuss all currently known components of the centrosome in comparison to other centrosomes of animals and yeasts.

Citing Articles

Nuclear Envelope Dynamics in Amoebae.

Graf R, Batsios P, Grafe M, Meyer I, Mitic K Cells. 2025; 14(3).

PMID: 39936978 PMC: 11816917. DOI: 10.3390/cells14030186.

Dynamic Mitotic Localization of the Centrosomal Kinases CDK1, Plk, AurK, and Nek2 in .

Kruger S, Pfaff N, Graf R, Meyer I Cells. 2024; 13(18.

PMID: 39329697 PMC: 11430746. DOI: 10.3390/cells13181513.

Temporal Changes in Nuclear Envelope Permeability during Semi-Closed Mitosis in Amoebae.

Mitic K, Meyer I, Graf R, Grafe M Cells. 2023; 12(10).

PMID: 37408214 PMC: 10216430. DOI: 10.3390/cells12101380.

Centrosome Positioning in Migrating Cells.

Ishikawa-Ankerhold H, Kroll J, van den Heuvel D, Renkawitz J, Muller-Taubenberger A Cells. 2022; 11(11).

PMID: 35681473 PMC: 9179490. DOI: 10.3390/cells11111776.

spastin is involved in nuclear envelope dynamics during semi-closed mitosis.

Schweigel U, Batsios P, Muller-Taubenberger A, Graf R, Grafe M Nucleus. 2022; 13(1):144-154.

PMID: 35298348 PMC: 8932920. DOI: 10.1080/19491034.2022.2047289.

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