Changes in Nutritional Outcomes After Sleeve Gastrectomy: a Systematic Review and Meta-analysis

Overview

Journal Obes Surg

Date 2021 Oct 22

PMID 34677757

Citations 2

Authors

Yan Wang

Leizhen Duan

Xue Han

Jinjin Wang

Guoli Yan

Affiliations

Soon will be listed here.

Abstract

Purpose: The aim of this meta-analysis is to evaluate the changes in nutritional indicators in individuals with obesity before and after SG.

Materials And Methods: A systematic retrieval of the available literature was performed using PubMed, Embase, Web of Science, and Chinese National Knowledge Infrastructure databases. The following indicators were evaluated: serum 25-hydroxyvitamin D [25(OH)D], calcium, phosphorus, iron, vitamin B12, folate, magnesium, and zinc from pre-operation to post-operation.

Results: A total of 38 studies met inclusion criteria. A significant increase was observed in serum 25(OH)D (SMD = 0.70, 95%CI 0.38 to 1.02, P < 0.001), phosphorus (SMD = 0.40, 95%CI 0.14 to 0.67, P = 0.003), iron (SMD = 0.50, 95%CI 0.38 to 0.62, P < 0.001), and folate (SMD = 0.37, 95%CI 0.09 to 0.65, P = 0.01) after SG. Nevertheless, the increasing trend of serum phosphorus (P = 0.143) and folate (P = 0.774) disappeared in the unprescribed subgroup. A significant decrease in serum zinc (SMD = - 0.41, 95%CI - 0.81 to - 0.01, P = 0.044) was found after SG. No significant changes in serum calcium (SMD = 0.08, 95%CI - 0.09 to 0.25, P = 0.372), vitamin B12 (SMD = 0.10, 95%CI - 0.13 to 0.33, P = 0.398), and magnesium (SMD = 0.24, 95%CI - 0.10 to 0.58, P = 0.169) were observed. However, a significant decrease in serum calcium (P = 0.042) and vitamin B12 (P = 0.037) was found in the unprescribed subgroup.

Conclusions: Serum 25(OH)D, phosphorus, iron, and folate levels improved after a careful monitoring and due to a rigorous supplementation. The optimal dose of calcium, magnesium, and zinc supplementation has yet to be established; therefore, a broader supplementation of trace elements and minerals has to be suggested.

Citing Articles

Changes in Nutritional Outcomes After Roux-en-Y Gastric Bypass: A Systematic Review and Meta-Analysis.

Duan L, Wang Y, Cheng L, Wang J Obes Surg. 2024; 34(6):2116-2129.

PMID: 38662252 DOI: 10.1007/s11695-024-07232-2.

The Rapid Changes in Bodyweight and Glycemic Control Are Determined by Pre-status After Bariatric Surgery in Both Genders in Young Chinese Individuals.

Wen S, Gong M, Wang T, Zhou M, Dong M, Li Y Cureus. 2023; 15(10):e46603.

PMID: 37937018 PMC: 10626214. DOI: 10.7759/cureus.46603.

References

Koliaki C, Liatis S, Kokkinos A . Obesity and cardiovascular disease: revisiting an old relationship. Metabolism. 2018; 92:98-107. DOI: 10.1016/j.metabol.2018.10.011. View

Walsh J, Vilaca T . Obesity, Type 2 Diabetes and Bone in Adults. Calcif Tissue Int. 2017; 100(5):528-535. PMC: 5394147. DOI: 10.1007/s00223-016-0229-0. View

Avgerinos K, Spyrou N, Mantzoros C, Dalamaga M . Obesity and cancer risk: Emerging biological mechanisms and perspectives. Metabolism. 2018; 92:121-135. DOI: 10.1016/j.metabol.2018.11.001. View

Fruh S . Obesity: Risk factors, complications, and strategies for sustainable long-term weight management. J Am Assoc Nurse Pract. 2017; 29(S1):S3-S14. PMC: 6088226. DOI: 10.1002/2327-6924.12510. View

Singh R, Kumar P, Mahalingam K . Molecular genetics of human obesity: A comprehensive review. C R Biol. 2017; 340(2):87-108. DOI: 10.1016/j.crvi.2016.11.007. View

Apovian C . Obesity: definition, comorbidities, causes, and burden. Am J Manag Care. 2016; 22(7 Suppl):s176-85. View

Cardoso L, Rodrigues D, Gomes L, Carrilho F . Short- and long-term mortality after bariatric surgery: A systematic review and meta-analysis. Diabetes Obes Metab. 2017; 19(9):1223-1232. DOI: 10.1111/dom.12922. View

Sheng B, Truong K, Spitler H, Zhang L, Tong X, Chen L . The Long-Term Effects of Bariatric Surgery on Type 2 Diabetes Remission, Microvascular and Macrovascular Complications, and Mortality: a Systematic Review and Meta-Analysis. Obes Surg. 2017; 27(10):2724-2732. DOI: 10.1007/s11695-017-2866-4. View

Macano C, Nyasavajjala S, Brookes A, Lafaurie G, Riera M . Comparing quality of life outcomes between Laparoscopic Sleeve Gastrectomy and Laparoscopic Roux-en-Y Gastric Bypass using the RAND36 questionnaire. Int J Surg. 2017; 42:138-142. DOI: 10.1016/j.ijsu.2017.04.061. View

10.

Sridharan K, Kalayarasan R, Kamalanathan S, Sahoo J, Kar S, Nandhini L . Change in insulin resistance, beta cell function, glucagon-like peptide-1 and calcitonin levels two weeks after bariatric surgery. Diabetes Metab Syndr. 2019; 13(3):2142-2147. DOI: 10.1016/j.dsx.2019.05.002. View

11.

Bacci V, Silecchia G . Vitamin D status and supplementation in morbid obesity before and after bariatric surgery. Expert Rev Gastroenterol Hepatol. 2010; 4(6):781-94. DOI: 10.1586/egh.10.69. View

12.

Pucci A, Batterham R . Mechanisms underlying the weight loss effects of RYGB and SG: similar, yet different. J Endocrinol Invest. 2018; 42(2):117-128. PMC: 6394763. DOI: 10.1007/s40618-018-0892-2. View

13.

Benaiges D, Mas-Lorenzo A, Goday A, Ramon J, Chillaron J, Pedro-Botet J . Laparoscopic sleeve gastrectomy: More than a restrictive bariatric surgery procedure?. World J Gastroenterol. 2015; 21(41):11804-14. PMC: 4631978. DOI: 10.3748/wjg.v21.i41.11804. View

14.

Dix C, Bauer J, Wright O . A Systematic Review: Vitamin D Status and Sleeve Gastrectomy. Obes Surg. 2016; 27(1):215-225. DOI: 10.1007/s11695-016-2436-1. View

15.

Zarshenas N, Nacher M, Loi K, Jorgensen J . Investigating Nutritional Deficiencies in a Group of Patients 3 Years Post Laparoscopic Sleeve Gastrectomy. Obes Surg. 2016; 26(12):2936-2943. DOI: 10.1007/s11695-016-2211-3. View

16.

Al-Mutawa A, Al-Sabah S, Anderson A, Al-Mutawa M . Evaluation of Nutritional Status Post Laparoscopic Sleeve Gastrectomy-5-Year Outcomes. Obes Surg. 2017; 28(6):1473-1483. DOI: 10.1007/s11695-017-3041-7. View

17.

Duran I, Gulcelik N, Bulut B, Balci Z, Berker D, Guler S . Differences in Calcium Metabolism and Thyroid Physiology After Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Obes Surg. 2018; 29(2):705-712. DOI: 10.1007/s11695-018-3595-z. View

18.

Lancha A, Moncada R, Valenti V, Rodriguez A, Catalan V, Becerril S . Comparative effects of gastric bypass and sleeve gastrectomy on plasma osteopontin concentrations in humans. Surg Endosc. 2014; 28(8):2412-20. DOI: 10.1007/s00464-014-3490-1. View

19.

Guerrero-Perez F, Casajoana A, Gomez-Vaquero C, Virgili N, Lopez-Urdiales R, Hernandez-Montoliu L . Changes in Bone Mineral Density in Patients with Type 2 Diabetes After Different Bariatric Surgery Procedures and the Role of Gastrointestinal Hormones. Obes Surg. 2019; 30(1):180-188. DOI: 10.1007/s11695-019-04127-5. View

20.

Mihmanli M, Isil R, Isil C, Omeroglu S, Sayin P, Oba S . Effects of Laparoscopic Sleeve Gastrectomy on Parathyroid Hormone, Vitamin D, Calcium, Phosphorus, and Albumin Levels. Obes Surg. 2017; 27(12):3149-3155. DOI: 10.1007/s11695-017-2747-x. View