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Melioidosis-related Mycotic Aneurysm: Three Cases

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Journal IDCases
Date 2021 Oct 14
PMID 34646734
Citations 2
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Abstract

Background: Melioidosis-related mycotic aneurysm (MA) is rare but a potentially life-threatening disease with high morbidity and mortality rate.

Case Presentation: We report a case series of mycotic aneurysm caused by and the subsequent outcomes. Here, we illustrate their clinical characteristics, laboratory results, radiological findings, mode of therapies and clinical outcomes.

Conclusion: Melioidosis-associated MA may manifest in an atypical presentation. Its outcome is often lethal if antimicrobial therapy and surgical intervention are not offered promptly.

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References
1.
Currie B, Ward L, Cheng A . The epidemiology and clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study. PLoS Negl Trop Dis. 2010; 4(11):e900. PMC: 2994918. DOI: 10.1371/journal.pntd.0000900. View

2.
Lee S, Liu Y, Wang J, Wann S . Mycotic aneurysm due to Burkholderia pseudomallei. Clin Infect Dis. 1998; 26(4):1013-4. DOI: 10.1086/517640. View

3.
Chetchotisakd P, Chierakul W, Chaowagul W, Anunnatsiri S, Phimda K, Mootsikapun P . Trimethoprim-sulfamethoxazole versus trimethoprim-sulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): a multicentre, double-blind, non-inferiority, randomised controlled trial. Lancet. 2013; 383(9919):807-14. PMC: 3939931. DOI: 10.1016/S0140-6736(13)61951-0. View

4.
Wu H, Wang X, Zhou X, Wu Z, Wang Y, Pan M . Mycotic aneurysm secondary to melioidosis in China: A series of eight cases and a review of literature. PLoS Negl Trop Dis. 2020; 14(8):e0008525. PMC: 7446808. DOI: 10.1371/journal.pntd.0008525. View

5.
Sorelius K, Wanhainen A, Furebring M, Bjorck M, Gillgren P, Mani K . Nationwide Study of the Treatment of Mycotic Abdominal Aortic Aneurysms Comparing Open and Endovascular Repair. Circulation. 2016; 134(23):1822-1832. DOI: 10.1161/CIRCULATIONAHA.116.024021. View