» Articles » PMID: 34631049

Management of Portal Vein Thrombosis in Cirrhotic Patients Enlisted for Liver Transplantation: From Diagnosis to Treatment (Review)

Overview
Journal Biomed Rep
Specialty Biochemistry
Date 2021 Oct 11
PMID 34631049
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

Portal vein thrombosis (PVT) commonly occurs in patients with cirrhosis. Several classification systems of PVT have been proposed over the years reflecting the challenge in establishing a widely accepted system. To date, PVT has been considered an absolute contraindication for orthotopic liver transplantation (OLT) since it is associated with decreased graft survival and increased patient mortality. Nevertheless, the development of modern surgical techniques has enabled the inclusion of these candidates in OLT waiting lists, since their postoperative results are shown to be comparable to those of patients without PVT. The aim of the present review was to critically appraise the available treatment options for cirrhotic patients enlisted for liver transplantation in the setting of PVT.

Citing Articles

Management of Preoperative Recipient Portal Vein Thrombosis in Living-donor Liver Transplantation.

Rajendran V, Joy D, Sudheer Mohammed , Chandran B, Jacob M J Clin Exp Hepatol. 2025; 15(2):102445.

PMID: 39802411 PMC: 11714416. DOI: 10.1016/j.jceh.2024.102445.


A novel approach for portal system reconstruction in liver transplant patients with grade IV portal vein thrombosis: Case study and literature review.

Qu W, Zhu Z, Wei L Front Transplant. 2024; 1:922881.

PMID: 38994378 PMC: 11235255. DOI: 10.3389/frtra.2022.922881.


Portal Vein Thrombosis: State-of-the-Art Review.

Boccatonda A, Gentilini S, Zanata E, Simion C, Serra C, Simioni P J Clin Med. 2024; 13(5).

PMID: 38592411 PMC: 10932352. DOI: 10.3390/jcm13051517.


Portal vein thrombosis: Before, during, and after liver transplant.

Toth 3rd J, Barman P Clin Liver Dis (Hoboken). 2023; 22(1):14-17.

PMID: 37521185 PMC: 10378985. DOI: 10.1097/CLD.0000000000000067.


Portal vein-variceal anastomosis for portal vein inflow reconstruction in orthotopic liver transplantation: A case report and review of literature.

Gravetz A World J Transplant. 2022; 12(7):204-210.

PMID: 36051454 PMC: 9331412. DOI: 10.5500/wjt.v12.i7.204.

References
1.
Magistri P, Tarantino G, Olivieri T, Pecchi A, Ballarin R, Di Benedetto F . Extra-Anatomic Jump Graft from the Right Colic Vein: A Novel Technique to Manage Portal Vein Thrombosis in Liver Transplantation. Case Rep Surg. 2018; 2018:4671828. PMC: 5821981. DOI: 10.1155/2018/4671828. View

2.
Manzia T, Fazzolari L, Manuelli M, Pellicciaro M, Baiocchi L, Tisone G . Liver transplantation in a patient with complete portal vein thrombosis, is there a surgical way out? A case report. Ann Med Surg (Lond). 2016; 11:5-8. PMC: 5011162. DOI: 10.1016/j.amsu.2016.08.002. View

3.
Nikitin D, Jennings L, Khan T, Vasani S, Ruiz R, Sanchez E . Twenty years' follow-up of portal vein conduits in liver transplantation. Liver Transpl. 2009; 15(4):400-6. DOI: 10.1002/lt.21698. View

4.
Vianna R, Mangus R, Kubal C, Fridell J, Beduschi T, Tector A . Multivisceral transplantation for diffuse portomesenteric thrombosis. Ann Surg. 2012; 255(6):1144-50. DOI: 10.1097/SLA.0b013e31825429c0. View

5.
Sarin S, Philips C, Kamath P, Choudhury A, Maruyama H, Nery F . Toward a Comprehensive New Classification of Portal Vein Thrombosis in Patients With Cirrhosis. Gastroenterology. 2016; 151(4):574-577.e3. DOI: 10.1053/j.gastro.2016.08.033. View