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Recognizing and Managing Adverse Events in Y-90 Radioembolization

Overview
Specialty Radiology
Date 2021 Oct 11
PMID 34629713
Citations 3
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Abstract

Transarterial radioembolization using yttrium-90 (Y-90) microspheres is an important therapy in the management of unresectable primary liver tumors or hepatic metastases. While radioembolization is generally well-tolerated, it is not free from adverse events, and familiarity with the prevention and treatment of radioembolization-specific complications is an important component of patient care. This article aims to review radioembolization-specific toxicities stratified by hepatic, extrahepatic, and systemic effects, with a focus on preventing and mitigating radioembolization-induced morbidity.

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References
1.
Kallini J, Gabr A, Thorlund K, Balijepalli C, Ayres D, Kanters S . Comparison of the Adverse Event Profile of TheraSphere with SIR-Spheres for the Treatment of Unresectable Hepatocellular Carcinoma: A Systematic Review. Cardiovasc Intervent Radiol. 2017; 40(7):1033-1043. DOI: 10.1007/s00270-017-1594-4. View

2.
Dezarn W, Cessna J, DeWerd L, Feng W, Gates V, Halama J . Recommendations of the American Association of Physicists in Medicine on dosimetry, imaging, and quality assurance procedures for 90Y microsphere brachytherapy in the treatment of hepatic malignancies. Med Phys. 2011; 38(8):4824-45. DOI: 10.1118/1.3608909. View

3.
Thuring J, Zimmermann M, Bruners P, Pedersoli F, Schulze-Hagen M, Barzakova E . Short-Term Oral Sorafenib for Therapy of Intratumoral Shunts of Hepatocellular Carcinoma to Enable Intraarterial Treatment. Cardiovasc Intervent Radiol. 2019; 42(10):1494-1499. PMC: 6715807. DOI: 10.1007/s00270-019-02294-7. View

4.
Padia S, Lewandowski R, Johnson G, Sze D, Ward T, Gaba R . Radioembolization of Hepatic Malignancies: Background, Quality Improvement Guidelines, and Future Directions. J Vasc Interv Radiol. 2016; 28(1):1-15. DOI: 10.1016/j.jvir.2016.09.024. View

5.
Gabr A, Abouchaleh N, Ali R, Baker T, Caicedo J, Katariya N . Outcomes of Surgical Resection after Radioembolization for Hepatocellular Carcinoma. J Vasc Interv Radiol. 2018; 29(11):1502-1510.e1. DOI: 10.1016/j.jvir.2018.06.027. View