High Level Xylitol Production by Pichia Fermentans Using Non-detoxified Xylose-rich Sugarcane Bagasse and Olive Pits Hydrolysates

Overview

Journal Bioresour Technol

Specialty Biophysics

Date 2021 Sep 30

PMID 34592613

Citations 10

Authors

Vivek Narisetty

Eulogio Castro

Sumit Durgapal

Frederic Coulon

Samuel Jacob

Dinesh Kumar

Mukesh Kumar Awasthi

Kamal Kishore Pant

Binod Parameswaran

Vinod Kumar

Affiliations

Soon will be listed here.

Abstract

Hemicellulosic sugars, the overlooked fraction of lignocellulosic residues can serve as potential and cost-effective raw material that can be exploited for xylitol production. Xylitol is a top platform chemical with applications in food and pharmaceutical industries. Sugarcane bagasse (SCB) and olive pits (OP) are the major waste streams from sugar and olive oil industries, respectively. The current study evaluated the potential of Pichia fermentans for manufacturing of xylitol from SCB and OP hydrolysates through co-fermentation strategy. The highest xylitol accumulation was noticed with a glucose and xylose ratio of 1:10 followed by feeding with xylose alone. The fed-batch cultivation using pure xylose, SCB, and OP hydrolysates, resulted in xylitol accumulation of 102.5, 86.6 and 71.9 g/L with conversion yield of 0.78, 0.75 and 0.74 g/g, respectively. The non-pathogenic behaviour and ability to accumulate high xylitol levels from agro-industrial residues demonstrates the potential of P. fermentans as microbial cell factory.

Citing Articles

Co-substrate model development and validation on pure sugars and corncob hemicellulosic hydrolysate for xylitol production.

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Research progress in the biosynthesis of xylitol: feedstock evolution from xylose to glucose.

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Valorisation of corncob into furfuryl alcohol and furoic acid via chemoenzymatic cascade catalysis.

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Development of engineered Candida tropicalis strain for efficient corncob-based xylitol-ethanol biorefinery.

Singh A, Deeba F, Kumar M, Kumari S, Wani S, Paul T Microb Cell Fact. 2023; 22(1):201.

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Detoxification Approaches of Bagasse Pith Hydrolysate Affecting Xylitol Production by Rhodotorula mucilaginosa.

Garmaroody E, PahnehKolaei N, Ramezani O, Hamedi S Appl Biochem Biotechnol. 2023; 196(1):129-144.

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