Life in the Flame: Inflammation Sounds the Alarm for Suicide Risk

Overview

Journal Brain Behav Immun Health

Date 2021 Sep 30

PMID 34589761

Citations 7

Authors

Wen-Jie Yan

Chun-Lei Jiang

Wen-Jun Su

Affiliations

Soon will be listed here.

Abstract

As suicide became a critical issue in mental healthcare, the World Health Organization (WHO) presented a Mental Health Action Plan in 2013. Particularly, the plan set an explicit goal for suicide prevention, which called for 10% reduction in the suicide rate in member countries by 2020. Now the tough year of 2020 has passed by, many valuable breakthroughs on suicide research have emerged during these recent years. To some extent, a multi-stage system for the prediction and prevention of suicide is taking shape. Inflammatory biomarkers may have a promising future within this field.

Citing Articles

Distinct Effects of Major Affective Disorder Diagnoses and Suicidal Symptom Severity on Inhibitory Control Function and Proinflammatory Cytokines: Single-Site Analysis of 800 Adolescents and Adults.

Bai Y, Chen M, Hsu J, Huang H, Jeng J, Tsai S Int J Neuropsychopharmacol. 2024; 27(10).

PMID: 39283831 PMC: 11450626. DOI: 10.1093/ijnp/pyae043.

Relationship between serum inflammatory cytokines and suicide risk in patients with major depressive disorder.

Yang Y, Gu K, Li J Front Psychiatry. 2024; 15:1422511.

PMID: 38993383 PMC: 11236750. DOI: 10.3389/fpsyt.2024.1422511.

Cool the Inflamed Brain: A Novel Anti-inflammatory Strategy for the Treatment of Major Depressive Disorder.

Su W, Hu T, Jiang C Curr Neuropharmacol. 2023; 22(5):810-842.

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Fight the Fire: Association of Cytokine Genomic Markers and Suicidal Behavior May Pave the Way for Future Therapies.

Gonda X, Serafini G, Dome P J Pers Med. 2023; 13(7).

PMID: 37511694 PMC: 10381806. DOI: 10.3390/jpm13071078.

Suicidality in civilian women with PTSD: Possible link to childhood maltreatment, proinflammatory molecules, and their genetic variations.

Kawanishi H, Hori H, Yoshida F, Itoh M, Lin M, Niwa M Brain Behav Immun Health. 2023; 30:100650.

PMID: 37363341 PMC: 10285106. DOI: 10.1016/j.bbih.2023.100650.

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