Intracerebral Hemorrhage and Reversible Cerebral Vasoconstriction Syndrome in a Patient With COVID-19

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2021 Sep 30

PMID 34589319

Citations 3

Authors

Aswin Srinivasan

Branden C Wilson

Matthew Bear

Ammar Hasan

Obadah Ezzeldin

Salman Alim

Samer Elfallal

Xiang Fang

Mohamad Ezzeldin

Affiliations

Soon will be listed here.

Abstract

Neurological manifestations, such as encephalopathy, intracranial neuropathy, headache, and cognitive decline, are often presented in patients with COVID-19 infection. Since the onset of the pandemic, acute ischemic stroke associated with a hypercoagulable state caused by COVID-19 is increasingly being reported. Hemorrhagic stroke is also reported via poorly understood mechanisms. We report one of the first-ever cases of intraparenchymal hemorrhage, subarachnoid hemorrhage secondary to reversible cerebral vasoconstriction syndrome in a patient with COVID-19 infection.

Citing Articles

Clinical Characteristics of COVID-19-Related Reversible Cerebral Vasoconstriction Syndrome: A Systematic Review of Case Series.

Jung R, Oh Y, Choi S, Park M, Ha H, Kim N J Clin Med. 2025; 14(2).

PMID: 39860493 PMC: 11765861. DOI: 10.3390/jcm14020487.

Headache Attributed to Reversible Cerebral Vasoconstriction Syndrome (RCVS).

Tentolouris-Piperas V, Lymperopoulos L, Tountopoulou A, Vassilopoulou S, Mitsikostas D Diagnostics (Basel). 2023; 13(17).

PMID: 37685270 PMC: 10487016. DOI: 10.3390/diagnostics13172730.

Posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome in patients with COVID-19 infection: is there a link? A systematic review and case report analysis.

Bonura A, Iaccarino G, Rossi S, Capone F, Motolese F, Calandrelli R J Neurol. 2023; 270(6):2826-2852.

PMID: 37014421 PMC: 10071475. DOI: 10.1007/s00415-023-11684-4.

Cerebral microvascular complications associated with SARS-CoV-2 infection: How did it occur and how should it be treated?.

Omidian N, Mohammadi P, Sadeghalvad M, Mohammadi-Motlagh H Biomed Pharmacother. 2022; 154:113534.

PMID: 35994816 PMC: 9381434. DOI: 10.1016/j.biopha.2022.113534.

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