Migratory Birds Travelling to Bangladesh Are Potential Carriers of Multi-drug Resistant Spp., Spp., and Spp

Overview

Journal Saudi J Biol Sci

Specialty Biology

Date 2021 Sep 30

PMID 34588913

Citations 21

Authors

Md Saiful Islam

Anamika Paul

Mithun Talukder

Krishna Roy

Md Abdus Sobur

Samina Ievy

Md Mehedi Hasan Nayeem

Saifur Rahman

K H M Nazmul Hussain Nazir

Muhammad Tofazzal Hossain

Md Tanvir Rahman

Affiliations

Soon will be listed here.

Abstract

Antimicrobial resistance (AMR) is a major health crisis globally. Migratory birds could be a potential source for antibiotic resistant (ABR) bacteria. Not much is known about their role in the transmission of ABR in Bangladesh. In this study, a total of 66 freshly dropped fecal materials of migratory birds were analyzed. Bacterial isolation and identification were based on cultural properties, biochemical tests, and polymerase chain reaction (PCR). The disk diffusion method was employed to evaluate antibiogram profiles. By PCR, out of 66 samples, the detection rate of spp. (60.61%; 95% confidence interval: 48.55-71.50%) was found significantly higher than spp. (21.21%; 95% CI: 13.08-32.51%) and spp. (39.40%; 95% CI: 28.50-51.45%). isolates were frequently found resistant (100-40%) to ampicillin, streptomycin, meropenem, erythromycin, and gentamicin; isolates were frequently resistant (72-43%) to chloramphenicol, tetracycline, ampicillin, streptomycin, and erythromycin; and spp. isolates were frequently resistant (77-31%) to vancomycin, ampicillin, erythromycin, tetracycline, and streptomycin. In addition, 60% (95% CI: 44.60-73.65%) spp., 85.71% (95% CI: 60.06-97.46%) spp., and 76.92% (95% CI: 57.95-88.97%) spp. isolates were multi-drug resistant (MDR) in nature. Three isolates (one from each bacterium) were found resistant against six classes of antibiotics. The bivariate analysis revealed strong associations (both positive and negative) between several antibiotic pairs which were resistant to isolated organisms. To the best of our knowledge, this is the first study in detecting MDR spp., spp., and spp. from migratory birds travelling to Bangladesh. Frequent detection of MDR bacteria from migratory birds travelling to Bangladesh suggests that these birds have the potential to carry and spread ABR bacteria and could implicate potential risks to public health. We recommend that these birds should be kept under an AMR surveillance program to minimize the potential risk of contamination of the environment with ABR as well as to reduce their hazardous impacts on health.

Citing Articles

Prevalence of common diarrheagenic enterobacteriaceae in Iran (2000-2023): a systematic review and meta-analysis.

Derakhshan-Sefidi M, Eidy F, Nadi-Ravandi S, Bagheri-Josheghani S, Mirfakhraei M BMC Gastroenterol. 2025; 25(1):43.

PMID: 39881226 PMC: 11776153. DOI: 10.1186/s12876-025-03634-3.

Assessment of prevalence, antibiotic resistance, and virulence profiles of biofilm-forming isolated from raw seafood in Bangladesh.

Ullah M, Islam M, Ferdous F, Rana M, Hassan J, Rahman M Heliyon. 2024; 10(20):e39294.

PMID: 39640770 PMC: 11620263. DOI: 10.1016/j.heliyon.2024.e39294.

Virulence and Antimicrobial Resistance Patterns of Salmonella spp. Recovered From Migratory and Captive Wild Birds.

Begum R, Asha N, Dipu D, Roy M, Rahman A, Rahman Chowdhury M Vet Med Sci. 2024; 10(6):e70102.

PMID: 39494993 PMC: 11533216. DOI: 10.1002/vms3.70102.

Role of migratory birds as a risk factor for the transmission of multidrug resistant Salmonella enterica and Escherichia coli to broiler poultry farms and its surrounding environment.

Tawakol M, Nabil N, Samir A, Hassan H, Reda R, Abdelaziz O BMC Res Notes. 2024; 17(1):314.

PMID: 39420393 PMC: 11487717. DOI: 10.1186/s13104-024-06958-7.

Antibiotic resistance risk assessment in Mymensingh, Bangladesh: Current scenario from human-animal-environmental interfaces viewpoint.

Al Noman Z, Anika T, Safa U, Alam S, Dey S, Bhuiyan M Heliyon. 2024; 10(15):e35878.

PMID: 39170164 PMC: 11337057. DOI: 10.1016/j.heliyon.2024.e35878.

References

Guenther S, Aschenbrenner K, Stamm I, Bethe A, Semmler T, Stubbe A . Comparable high rates of extended-spectrum-beta-lactamase-producing Escherichia coli in birds of prey from Germany and Mongolia. PLoS One. 2013; 7(12):e53039. PMC: 3534101. DOI: 10.1371/journal.pone.0053039. View

Cardoso M, Lemos L, Roges E, de Moura J, Tavares D, Matias C . A comprehensive survey of Aeromonas sp. and Vibrio sp. in seabirds from southeastern Brazil: outcomes for public health. J Appl Microbiol. 2018; 124(5):1283-1293. DOI: 10.1111/jam.13705. View

Stepien-Pysniak D, Hauschild T, Nowaczek A, Marek A, Dec M . WILD BIRDS AS A POTENTIAL SOURCE OF KNOWN AND NOVEL MULTILOCUS SEQUENCE TYPES OF ANTIBIOTIC-RESISTANT ENTEROCOCCUS FAECALIS. J Wildl Dis. 2017; 54(2):219-228. DOI: 10.7589/2017-05-118. View

Ramey A, Hernandez J, Tyrlov V, Uher-Koch B, Schmutz J, Atterby C . Antibiotic-Resistant Escherichia coli in Migratory Birds Inhabiting Remote Alaska. Ecohealth. 2017; 15(1):72-81. DOI: 10.1007/s10393-017-1302-5. View

Santos T, Silva N, Igrejas G, Rodrigues P, Micael J, Rodrigues T . Dissemination of antibiotic resistant Enterococcus spp. and Escherichia coli from wild birds of Azores Archipelago. Anaerobe. 2013; 24:25-31. DOI: 10.1016/j.anaerobe.2013.09.004. View

Fu S, Hao J, Yang Q, Lan R, Wang Y, Ye S . Long-distance transmission of pathogenic Vibrio species by migratory waterbirds: a potential threat to the public health. Sci Rep. 2019; 9(1):16303. PMC: 6841736. DOI: 10.1038/s41598-019-52791-5. View

Chadfield M, Christensen J, Christensen H, Bisgaard M . Characterization of streptococci and enterococci associated with septicaemia in broiler parents with a high prevalence of endocarditis. Avian Pathol. 2005; 33(6):610-7. DOI: 10.1080/03079450400013089. View

Dolejska M, Bierosova B, Kohoutova L, Literak I, Cizek A . Antibiotic-resistant Salmonella and Escherichia coli isolates with integrons and extended-spectrum beta-lactamases in surface water and sympatric black-headed gulls. J Appl Microbiol. 2009; 106(6):1941-50. DOI: 10.1111/j.1365-2672.2009.04155.x. View

Tsiodras S, Kelesidis T, Kelesidis I, Bauchinger U, Falagas M . Human infections associated with wild birds. J Infect. 2007; 56(2):83-98. PMC: 7172416. DOI: 10.1016/j.jinf.2007.11.001. View

10.

Najdenski H, Dimova T, Zaharieva M, Nikolov B, Petrova-Dinkova G, Dalakchieva S . Migratory birds along the Mediterranean - Black Sea Flyway as carriers of zoonotic pathogens. Can J Microbiol. 2018; 64(12):915-924. DOI: 10.1139/cjm-2017-0763. View

11.

Sweeney M, Lubbers B, Schwarz S, Watts J . Applying definitions for multidrug resistance, extensive drug resistance and pandrug resistance to clinically significant livestock and companion animal bacterial pathogens. J Antimicrob Chemother. 2018; 73(6):1460-1463. DOI: 10.1093/jac/dky043. View

12.

Rahman M, Sobur M, Islam M, Ievy S, Hossain M, El Zowalaty M . Zoonotic Diseases: Etiology, Impact, and Control. Microorganisms. 2020; 8(9). PMC: 7563794. DOI: 10.3390/microorganisms8091405. View

13.

Diaz-Sanchez S, Sanchez S, Ewers C, Hofle U . Occurrence of avian pathogenic Escherichia coli and antimicrobial-resistant E. coli in red-legged partridges (Alectoris rufa): sanitary concerns of farming. Avian Pathol. 2012; 41(4):337-44. DOI: 10.1080/03079457.2012.687101. View

14.

BAUER A, KIRBY W, SHERRIS J, Turck M . Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966; 45(4):493-6. View

15.

Rashid M, Rakib M, Hasan B . Antimicrobial-resistant and ESBL-producing Escherichia coli in different ecological niches in Bangladesh. Infect Ecol Epidemiol. 2015; 5:26712. PMC: 4507753. DOI: 10.3402/iee.v5.26712. View

16.

Atterby C, Ramey A, Hall G, Jarhult J, Borjesson S, Bonnedahl J . Increased prevalence of antibiotic-resistant E. coli in gulls sampled in Southcentral Alaska is associated with urban environments. Infect Ecol Epidemiol. 2016; 6:32334. PMC: 5030259. DOI: 10.3402/iee.v6.32334. View

17.

Ievy S, Islam M, Sobur M, Talukder M, Rahman M, Khan M . Molecular Detection of Avian Pathogenic (APEC) for the First Time in Layer Farms in Bangladesh and Their Antibiotic Resistance Patterns. Microorganisms. 2020; 8(7). PMC: 7409187. DOI: 10.3390/microorganisms8071021. View

18.

Lin Y, Dong X, Sun R, Wu J, Tian L, Rao D . Migratory birds-one major source of environmental antibiotic resistance around Qinghai Lake, China. Sci Total Environ. 2020; 739:139758. PMC: 7260505. DOI: 10.1016/j.scitotenv.2020.139758. View

19.

Zereen F, Akter S, Sobur M, Hossain M, Rahman M . Molecular detection of from human stool collected from SK Hospital, Mymensingh, and their antibiogram. J Adv Vet Anim Res. 2019; 6(4):451-455. PMC: 6882716. DOI: 10.5455/javar.2019.f367. View

20.

Islam M, Mehedi Hasan Nayeem M, Sobur M, Ievy S, Islam M, Rahman S . Virulence Determinants and Multidrug Resistance of Isolated from Migratory Birds. Antibiotics (Basel). 2021; 10(2). PMC: 7919266. DOI: 10.3390/antibiotics10020190. View