Commandeering the Mammalian Ago2 MiRNA Network: a Newly Discovered Mechanism of Helminth Immunomodulation

MicroRNAs (miRNAs) are a class of noncoding RNAs that contribute to a broad range of biological processes through post-transcriptional regulation of gene expression. Helminths exploit this system to target mammalian gene expression, to modulate the host immune response. Recent discoveries have shed new light on the mechanisms involved.