Heteroelement Analogues of Benzoxaborole and Related Ring Expanded Systems

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2021 Sep 28

PMID 34576937

Citations 3

Authors

Krzysztof Nowicki

Piotr Pacholak

Sergiusz Lulinski

Affiliations

Soon will be listed here.

Abstract

The review covers the chemistry of organoboron heterocycles structurally related to benzoxaboroles where one of the carbon atoms in a boracycle or a fused benzene ring is replaced by a heteroelement such as boron, silicon, tin, nitrogen, phosphorus, or iodine. Related ring expanded systems including those based on naphthalene and biphenyl cores are also described. The information on synthetic methodology as well as the basic structural and physicochemical characteristics of these emerging heterocycles is complemented by a presentation of their potential applications in organic synthesis and medicinal chemistry, the latter aspect being mostly focused on the promising antimicrobial activity of selected compounds.

Citing Articles

Exploiting thiol-functionalized benzosiloxaboroles for achieving diverse substitution patterns - synthesis, characterization and biological evaluation of promising antibacterial agents.

Nowicki K, Krajewska J, Stepniewski T, Wielechowska M, Winska P, Kaczmarczyk A RSC Med Chem. 2024; 15(5):1751-1772.

PMID: 38784477 PMC: 11110727. DOI: 10.1039/d4md00061g.

Incorporation of a Boron-Nitrogen Covalent Bond Improves the Charge-Transport and Charge-Transfer Characteristics of Organoboron Small-Molecule Acceptors for Organic Solar Cells.

Yang J, Ding W, Li Q, Li Z Molecules. 2023; 28(2).

PMID: 36677871 PMC: 9861936. DOI: 10.3390/molecules28020811.

Oxazoline scaffold in synthesis of benzosiloxaboroles and related ring-expanded heterocycles: diverse reactivity, structural peculiarities and antimicrobial activity.

Krajewska J, Nowicki K, Durka K, Marek-Urban P, Winska P, Stepniewski T RSC Adv. 2022; 12(36):23099-23117.

PMID: 36090419 PMC: 9379557. DOI: 10.1039/d2ra03910a.

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