Impact of Umbilical Cord Arterial PH, Gestational Age, and Birth Weight on Neurodevelopmental Outcomes for Preterm Neonates

Overview

Journal PeerJ

Specialties Biology
Environmental Health
General Medicine

Date 2021 Sep 27

PMID 34567841

Citations 3

Authors

Roksana Malak

Dorota Sikorska

Marta Rosolek

Ewa Baum

Ewa Mojs

Przemyslaw Daroszewski

Monika Matecka

Brittany Fechner

Wlodzimierz Samborski

Affiliations

Soon will be listed here.

Abstract

Background: The aim of this study was to determine the impact of umbilical cord arterial pH, gestational age, and birth weight on neurodevelopmental outcomes for preterm neonates.

Methods: We examined 112 neonates. Inclusion criteria were: Saturations greater than 88%, and heart rates between 100-205 beats per minute.

Measurements: We assessed several neurodevelopmental factors as part of the Brazelton Neonatal Behavioral Assessment Scale (NBAS), 4th edition, such as asymmetric tonic neck reflex (ATNR), motor maturity, response to sensory stimuli, habituation, and state regulation. Initial assessment parameters such as APGAR score and umbilical cord arterial pH were used to assess neonates.

Results: We found a strong correlation between the presence of the sucking reflex and umbilical cord arterial pH ( = 0.32; = 0.018981). Umbilical cord arterial pH was also correlated with the presence of asymmetric tonic neck reflex ( = 0.27; = 0.047124), cost of attention ( = 0.31; = 0.025381) and general motor maturity ( = 0.34; = 0.011741).

Conclusions: We found that the sucking reflex may be affected in infants with low umbilical cord arterial pH values. Practitioners and parents can use the NBAS to help determine neurodevelopmental factors and outcomes in preterm infants, possibly leading to safer and more effective feeding practices and interventions.

Citing Articles

The Impact of Total Deceleration Area and Fetal Growth on Neonatal Acidemia in Vacuum Extraction Deliveries.

Cohen G, Ravid D, Gnaiem N, Gluska H, Schreiber H, Haleluya N Children (Basel). 2023; 10(5).

PMID: 37238325 PMC: 10217050. DOI: 10.3390/children10050776.

The Importance of Monitoring Neurodevelopmental Outcomes for Preterm Infants: A Comparison of the AIMS, GMA, Pull to Sit Maneuver and ASQ-3.

Malak R, Fechner B, Stankowska M, Wiechec K, Szczapa T, Kasperkowicz J J Clin Med. 2022; 11(21).

PMID: 36362524 PMC: 9657223. DOI: 10.3390/jcm11216295.

The Influence of Parent Education on the Neurobehavior and Sucking Reflexes of Very Preterm Infants.

Malak R, Wiechec K, Fechner B, Szczapa T, Kasperkowicz J, Matthews-Kozanecka M Brain Sci. 2022; 12(7).

PMID: 35884647 PMC: 9313055. DOI: 10.3390/brainsci12070840.

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