First Human Case of Catheter-related Blood Stream Infection Caused by Staphylococcus Schleiferi Subspecies Coagulans: a Case Report and Literature Review

Overview

Journal Ann Clin Microbiol Antimicrob

Publisher Biomed Central

Specialties Infectious Diseases
Microbiology

Date 2021 Sep 26

PMID 34563226

Citations 5

Authors

Tatsuya Kobayashi

Mahoko Ikeda

Yuki Ohama

Koji Murono

Kazuhiko Ikeuchi

Satoshi Kitaura

Koh Okamoto

Shu Okugawa

Soichiro Ishihara

Kyoji Moriya

Affiliations

Soon will be listed here.

Abstract

Background: Staphylococcus schleiferi is a gram-positive pathogenic coccus which causes canine skin and ear infections. Only four cases of human infection caused by Staphylococcus schleiferi subspecies coagulans have been reported. Herein, we present the first case of catheter-related bloodstream infection caused by S. schleiferi subspecies coagulans.

Case Presentation: A 62-year-old Japanese man was admitted to our hospital for examination of sigmoid colon tumor. During hospitalization, he had fever, shaking chills, and swelling at the peripheral venous catheter insertion site. Two sets of blood cultures were positive for S. schleiferi subspecies coagulans which was confirmed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), 16S ribosomal RNA sequencing and the coagulase test. The patient was successfully treated without relapse.

Conclusion: To our knowledge, this is the first report of catheter-related bloodstream infection caused by S. schleiferi subspecies coagulans. S. schleiferi subsp. coagulans can be pathogenic in humans, and MALDI-TOF MS can contribute to accurate identification of S. schleiferi subspecies coagulans.

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