Pathogenesis of Autoimmune Hepatitis
Overview
Affiliations
Autoimmune hepatitis (AIH) is a chronic progressive liver disease whose etiology and pathogenesis are not yet clear. It is currently believed that the occurrence of AIH is closely related to genetic susceptibility and immune abnormalities, and other factors such as environment, viral infection and drugs that may cause immune dysfunction. This article reviews the pathogenesis of AIH and describes the latest research results in the past 5 years.
Inflammasome Molecular Insights in Autoimmune Diseases.
Neamtu M, Bild V, Vasincu A, Arcan O, Bulea D, Ababei D Curr Issues Mol Biol. 2024; 46(4):3502-3532.
PMID: 38666950 PMC: 11048795. DOI: 10.3390/cimb46040220.
Manganese Exacerbates ConA-Induced Liver Inflammation via the cGAS-STING Signaling Pathway.
Saimaier K, Han S, Lv J, Zhuang W, Xie L, Liu G Inflammation. 2023; 47(1):333-345.
PMID: 37805951 DOI: 10.1007/s10753-023-01912-4.
SARS-CoV-2-Induced Autoimmune Hepatitis.
Martini N, Singla P, Arbuckle E, Goyal G, Liu Q, Santos-Zabala M Cureus. 2023; 15(5):e38932.
PMID: 37309335 PMC: 10257862. DOI: 10.7759/cureus.38932.
Domerecka W, Kowalska-Kepczynska A, Homa-Mlak I, Michalak A, Mlak R, Mazurek M Cells. 2022; 11(16).
PMID: 36010631 PMC: 9406892. DOI: 10.3390/cells11162554.
Domerecka W, Homa-Mlak I, Mlak R, Michalak A, Wilinska A, Kowalska-Kepczynska A J Clin Med. 2022; 11(8).
PMID: 35456267 PMC: 9026397. DOI: 10.3390/jcm11082174.