Acute COVID-19 Infection Associated With Necrotizing Disseminated Acute Leukoencephalopathy and Brain Microhemorrhages in a Pediatric Patient

Overview

Journal Pediatr Infect Dis J

Specialty Pediatrics

Date 2021 Sep 17

PMID 34533490

Citations 2

Authors

Camila de Avila

Luis F Rauseo Lopez

Yamini Mandelia

Affiliations

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Abstract

We present a case of a 14-year-old, previously healthy female, admitted with acute coronavirus disease 2019 infection and new-onset seizures secondary to virus-associated necrotizing disseminated acute leukoencephalopathy. Her symptoms resolved completely with intravenous immunoglobulin and steroids. Pathophysiology and prognosis of neurologic manifestations of coronavirus disease 2019 remain unclear.

Citing Articles

Acute necrotizing encephalopathy in children with COVID-19: a retrospective study of 12 cases.

Lin X, Wang Y, Li X, Abdalla M, Zhang F, Dong C Front Neurol. 2023; 14:1184864.

PMID: 37602239 PMC: 10433176. DOI: 10.3389/fneur.2023.1184864.

Neurological Manifestations of Coronavirus Disease 2019 and Mpox in Pediatric Patients and Their Management: A State-of-the-Art Systematic Review.

Deb N, Roy P, Biswakarma A, Mary T, Mahajan S, Khan J Pediatr Neurol. 2023; 146:65-78.

PMID: 37441883 PMC: 10195769. DOI: 10.1016/j.pediatrneurol.2023.05.011.