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Antibacterial Activities of Phytofabricated ZnO and CuO NPs by Leaf/Flower Mixture Extract Against Antibiotic Resistant Bacteria

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Journal Adv Pharm Bull
Date 2021 Sep 13
PMID 34513624
Citations 9
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Abstract

In this study, leaf/flower aqueous extract of medicinal plant species was used to synthesize ZnO and CuO nanoparticles (NPs) as a cost-effective, one-step, and eco-friendly method. Physicochemical properties of both metal oxide NPs (MONPs) were determined by UV-Vis spectroscopy, X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscope (SEM) and energy dispersive X-ray (EDX) techniques. Phytofabricated ZnONPs and CuNPs illustrated 65.02±7.55 and 26.92±4.7 nm with antibacterial activities against antibiotic-resistant and . Higher antibacterial activities were observed for CuONPs compared with ZnONPs. Large surface area and more reactivity resulted from smaller size as well as higher production of reactive oxygen species (ROS) were considered to antibacterial efficiency of CuONPs against antibiotic-resistant and .

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