» Articles » PMID: 34506449

Prevalence of Vitamin D Deficiency Among Patients of Acute Coronary Syndrome in a Tertiary Care Center of Eastern Nepal

Overview
Specialty General Medicine
Date 2021 Sep 10
PMID 34506449
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Introduction: Vitamin D deficiency is an emerging risk factor for cardiovascular diseases. Very few studies have been done to find out vitamin D deficiency status among cardiovascular patients in Nepalese setup. This research aims to find out the prevalence of vitamin D deficiency among patients of acute coronary syndrome admitted in a tertiary care center of eastern Nepal.

Methods: This was a descriptive cross-sectional study conducted among patients of acute coronary syndrome admitted in a tertiary care hospital from 1st February 2018 to 31st July 2018. Ethical clearence was taken from Institutional Review Committee of B.P. Koirala Institute of Health Sciences (Reference number: 259/074/075-IRC). Convenience sampling method was used. Data was entered in Microsoft Excel and analyzed using Statistical Package for the Social Sciences version 25. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.

Results: A total of 33 (64.7%) at 95% Confidence Interval (51.58-77.82) patients of acute coronary syndrome had vitamin D deficiency in our study with 19 (37.3%) having mild deficiency and 14 (27.4%) having moderate deficiency. None of the patients had severe vitamin D deficiency in our study. The mean vitamin D levels were lower in diabetics (23.57±9.28ng/ml) as compared to non-diabetics (31.91±12.50ng/ml), in hypertensive patients (24.36±7.67ng/ml) as compared to non-hypertensive patients (30.97±13.72ng/ml), and in patients with dyslipidemia (22.86±6.44ng/ml) as compared to those without dyslipidemia (37.68±13.15ng/ml).

Conclusions: Prevalence of vitamin D deficiency among patients of acute coronary syndrome in our study was comparable to various other homologous international studies.

Citing Articles

Non-Traditional Risk Factors as Contributors to Cardiovascular Disease.

Wang L, Lei J, Wang R, Li K Rev Cardiovasc Med. 2024; 24(5):134.

PMID: 39076735 PMC: 11273054. DOI: 10.31083/j.rcm2405134.

References
1.
Karur S, Veerappa V, Nanjappa M . Study of vitamin D deficiency prevalence in acute myocardial infarction. Int J Cardiol Heart Vessel. 2018; 3:57-59. PMC: 5801269. DOI: 10.1016/j.ijchv.2014.03.004. View

2.
Milazzo V, De Metrio M, Cosentino N, Marenzi G, Tremoli E . Vitamin D and acute myocardial infarction. World J Cardiol. 2017; 9(1):14-20. PMC: 5253190. DOI: 10.4330/wjc.v9.i1.14. View

3.
G R, Gupta A . Vitamin D deficiency in India: prevalence, causalities and interventions. Nutrients. 2014; 6(2):729-75. PMC: 3942730. DOI: 10.3390/nu6020729. View

4.
Vaidya A, Forman J . Vitamin D and hypertension: current evidence and future directions. Hypertension. 2010; 56(5):774-9. DOI: 10.1161/HYPERTENSIONAHA.109.140160. View

5.
Mozos I, Marginean O . Links between Vitamin D Deficiency and Cardiovascular Diseases. Biomed Res Int. 2015; 2015:109275. PMC: 4427096. DOI: 10.1155/2015/109275. View