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Novel Application of Light-Emitting Diode Therapy in the Treatment of Eyebrow Loss in Frontal Fibrosing Alopecia

Overview
Journal Sensors (Basel)
Publisher MDPI
Specialty Biotechnology
Date 2021 Sep 10
PMID 34502871
Citations 3
Authors
Affiliations
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Abstract

Background: Eyebrow loss in the course of frontal fibrosing alopecia (FFA) is becoming a growing issue among older females. It has a considerable negative impact on patients' quality of life. Since there is no standardized treatment, photobiomodulation with light-emitting diodes (LEDs) could be an option. Here we assess, for the first time, the efficacy of LED therapy in the treatment of eyebrow loss in females with FFA.

Methods: 16 female patients with FFA aged 60-74 years were enrolled in the study. LED therapy was performed once a week for a 10-week session. The LEDs' effectiveness was assessed at the baseline, after 10 irradiations, and 6 months after the end of treatment during a follow-up visit.

Results: The therapy was well tolerated. After 10 irradiations, the total eyebrow hair count increased significantly, as did the number of thick hairs and mid-thick hairs ( = 0.002, = 0.002, and = 0.044, respectively). During the follow-up visit, the total number of eyebrow hairs remained significantly higher than before treatment ( = 0.002).

Conclusion: The study revealed that LED therapy seems to be a novel and promising therapeutic option for eyebrow loss in patients with FFA. It is safe and well tolerated and leads to clinically and cosmetically acceptable improvement.

Citing Articles

Frontal Fibrosing Alopecia: An Update.

Messenger A, Asfour L, Harries M Am J Clin Dermatol. 2024; 26(2):155-174.

PMID: 39699852 DOI: 10.1007/s40257-024-00912-w.


Frontal Fibrosing Alopecia: A Comprehensive Guide for Cosmetic Dermatologists.

Landau M, Perez S, Tosti A Dermatol Ther (Heidelb). 2024; 15(1):15-29.

PMID: 39607666 PMC: 11785866. DOI: 10.1007/s13555-024-01311-z.


Eyebrow and Eyelash Alopecia: A Clinical Review.

Nguyen B, Hu J, Tosti A Am J Clin Dermatol. 2022; 24(1):55-67.

PMID: 36183302 PMC: 9870835. DOI: 10.1007/s40257-022-00729-5.

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