Diabetes and Pancreatic Cancer: Exploring the Two-way Traffic

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2021 Sep 9

PMID 34497428

Citations 27

Authors

Ayan Roy

Jayaprakash Sahoo

Sadishkumar Kamalanathan

Dukhabandhu Naik

Pazhanivel Mohan

Raja Kalayarasan

Affiliations

Soon will be listed here.

Abstract

Pancreatic cancer (PC) is often associated with a poor prognosis. Long-standing diabetes mellitus is considered as an important risk factor for its development. This risk can be modified by the use of certain antidiabetic medications. On the other hand, new-onset diabetes can signal towards an underlying PC in the elderly population. Recently, several attempts have been made to develop an effective clinical tool for PC screening using a combination of history of new-onset diabetes and several other clinical and biochemical markers. On the contrary, diabetes affects the survival after treatment for PC. We describe this intimate and complex two-way relationship of diabetes and PC in this review by exploring the underlying pathogenesis.

Citing Articles

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