Association of E484K Spike Protein Mutation With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Persons: Maryland, January-May 2021

Overview

Journal Clin Infect Dis

Publisher Oxford University Press

Specialty Infectious Diseases

Date 2021 Sep 2

PMID 34473242

Citations 7

Authors

Kenneth A Feder

Ami Patel

Venkata R Vepachedu

Catherine Dominguez

Eric N Keller

Liore Klein

Curi Kim

Tim Blood

Judie Hyun

Thelonious W Williams

Katherine A Feldman

Heba H Mostafa

C Paul Morris

Jacques Ravel

Monique Duwell

David Blythe

Robert Myers

Affiliations

Soon will be listed here.

Abstract

Among 9048 people infected with SARS-CoV-2 between January and May 2021 in Maryland, in regression-adjusted analysis, SARS-CoV-2 viruses carrying the spike protein mutation E484K were disproportionately prevalent among persons infected after full vaccination against COVID-19 compared with infected persons who were not fully vaccinated (aOR, 1.96; 95% CI: 1.36-2.83).

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