Oxidative Stress and the Neurovascular Unit

Overview

Journal Life (Basel)

Specialty Biology

Date 2021 Aug 27

PMID 34440511

Citations 33

Authors

Carmela Rinaldi

Luigi Donato

Simona Alibrandi

Concetta Scimone

Rosalia DAngelo

Antonina Sidoti

Affiliations

Soon will be listed here.

Abstract

The neurovascular unit (NVU) is a relatively recent concept that clearly describes the relationship between brain cells and their blood vessels. The components of the NVU, comprising different types of cells, are so interrelated and associated with each other that they are considered as a single functioning unit. For this reason, even slight disturbances in the NVU could severely affect brain homeostasis and health. In this review, we aim to describe the current state of knowledge concerning the role of oxidative stress on the neurovascular unit and the role of a single cell type in the NVU crosstalk.

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