Hydrocephalus in Myelomeningocele

Overview

Journal Childs Nerv Syst

Specialty Pediatrics

Date 2021 Aug 26

PMID 34435215

Citations 4

Authors

Sergio Cavalheiro

Marcos Devanir Silva da Costa

Mauricio Mendes Barbosa

Patricia Alessandra Dastoli

Jardel Nicacio Mendonca

Daniela Cavalheiro

Antonio Fernandes Moron

Affiliations

Soon will be listed here.

Abstract

Purpose: To investigate certain aspects of hydrocephalus in patients with myelomeningocele.

Methods: We retrospectively analyzed data of 1050 patients with myelomeningocele who underwent surgical treatment between June 1991 and June 2021. These patients were divided into three groups: group 1 consisted of patients who underwent surgery after the first 6 h of life, group 2 consisted of patients who underwent surgery within the first 6 h, and group 3 consisted of patients who underwent surgery during the fetal period and before 26 6/7 weeks of gestation.

Results: There were 125, 590, and 335 patients in groups 1, 2, and 3, respectively. In groups 1 and 2, 593 (83%) patients developed hydrocephalus after birth and required ventriculoperitoneal shunt placement in the maternity ward, mainly within the first 4 days of life. In contrast, in group 3, 24 (7.2%) patients required surgery to treat hydrocephalus after birth. Hydrocephalus was the primary cause of mortality in groups 1 and 2, with mortality rates of 35% and 10%, respectively. In group 3, the mortality rate was 0.8% and was not related to hydrocephalus.

Conclusion: The onset of hydrocephalus is directly related to myelomeningocele closure in neurosurgery.

Citing Articles

Meningomyelocele Perioperative Management in Neonatal: Case Series.

Suryaningrat F, Irenewati S, Sobana M, Kadi F, Primadi A, Yuniati T Children (Basel). 2024; 11(10).

PMID: 39457184 PMC: 11506514. DOI: 10.3390/children11101219.

Myelomeningocele: Long-Term Neurosurgical Management.

Marcati E, Meccariello G, Mastino L, Picano M, Giorgi P, Talamonti G Adv Tech Stand Neurosurg. 2024; 49:95-122.

PMID: 38700682 DOI: 10.1007/978-3-031-42398-7_6.

Decreased Maternal Morbidity and Improved Perinatal Results of Magnesium-Free Tocolysis and Classical Hysterotomy in Fetal Open Surgery for Myelomeningocele Repair: A Single-Center Study.

Zamlynski M, Olejek A, Horzelska E, Horzelski T, Zamlynski J, Bablok R Biomedicines. 2023; 11(2).

PMID: 36830929 PMC: 9953469. DOI: 10.3390/biomedicines11020392.

Somatic Development Disorders in Children and Adolescents Affected by Syndromes and Diseases Associated with Neurodysfunction and Hydrocephalus Treated/Untreated Surgically.

Perenc L, Guzik A, Podgorska-Bednarz J, Druzbicki M Int J Environ Res Public Health. 2022; 19(9).

PMID: 35565107 PMC: 9105737. DOI: 10.3390/ijerph19095712.

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