Analysis of Group B Streptococcal Types Associated with Disease in Human Infants and Adults

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 1978 Feb 1

PMID 344337

Citations 23

Authors

H W WILKINSON

Affiliations

Soon will be listed here.

Abstract

It is important to resolve existing differences of opinion regarding group B streptococcal type distribution in human disease because of the relevance of type prevalence to future programs of prevention. This report compares data obtained from typing 392 group B streptococci isolated from systemic infections in both infants and adults in the United States from 1972 through 1975. The data showed a substantial predominance of type III among strains isolated from cases of infant meningitis and from "late-onset" septicemia but did not confirm a prior report that type Ia causes most cases of "early-onset" infant septicemia. Type II was the predominant serotype among 11 cerebrospinal fluid isolates from adults. The fact that over one-fourth of the isolates were types other than Ia or III means that future epidemiological studies, including definition of immunological factors, must include all five group B types.

Citing Articles

Incidence and outcomes of neonatal group B streptococcal sepsis in Qatar-a multicentre study.

Thyvilayil S, Vellamgot A, Salameh K, Kurunthattilthazhe S, Elikkottil A, Dominguez L BMC Pediatr. 2025; 25(1):41.

PMID: 39825283 PMC: 11740512. DOI: 10.1186/s12887-025-05398-x.

Genome-Wide fitness analysis of group B Streptococcus in human amniotic fluid reveals a transcription factor that controls multiple virulence traits.

Dammann A, Chamby A, Catomeris A, Davidson K, Tettelin H, van Pijkeren J PLoS Pathog. 2021; 17(3):e1009116.

PMID: 33684178 PMC: 7971860. DOI: 10.1371/journal.ppat.1009116.

Inapparent Streptococcus agalactiae infection in adult/commercial tilapia.

Sun J, Fang W, Ke B, He D, Liang Y, Ning D Sci Rep. 2016; 6:26319.

PMID: 27215811 PMC: 4877633. DOI: 10.1038/srep26319.

Estimation of group B streptococcus type III polysaccharide-specific antibody concentrations in human sera is antigen dependent.

Bhushan R, Anthony B, Frasch C Infect Immun. 1998; 66(12):5848-53.

PMID: 9826364 PMC: 108740. DOI: 10.1128/IAI.66.12.5848-5853.1998.

Group B streptococcal meningitis presenting as stroke in a nondebilitated man.

Klassen H, Klassen M, Huncharek M Yale J Biol Med. 1995; 68(1-2):1-6.

PMID: 8748460 PMC: 2590844.

References

Anthony B, Okada D . The emergence of group B streptococci in infections of the newborn infant. Annu Rev Med. 1977; 28:355-69. DOI: 10.1146/annurev.me.28.020177.002035. View

Baker C . Group B streptococcal infections: is prevention possible. South Med J. 1976; 69(12):1527-9. DOI: 10.1097/00007611-197612000-00001. View

Bayer A, Chow A, Anthony B, Guze L . Serious infections in adults due to group B streptococci. Clinical and serotypic characterization. Am J Med. 1976; 61(4):498-503. DOI: 10.1016/0002-9343(76)90329-6. View

Baker C, Barrett F . Group B streptococcal infections in infants. The importance of the various serotypes. JAMA. 1974; 230(8):1158-60. View

WILKINSON H, Jones W . Radioimmunoassay for measuring antibodies specific for group B streptococcal types Ia, Ib, Ic, II, and III. J Clin Microbiol. 1976; 3(5):480-5. PMC: 274335. DOI: 10.1128/jcm.3.5.480-485.1976. View

Eickhoff T, Klein J, MORTIMER Jr E, Wehrle P . Letter: The issue of prophylaxis of neonatal group B streptococcal infections. J Pediatr. 1973; 83(6):1097-100. DOI: 10.1016/s0022-3476(73)80569-4. View

Franciosi R, Knostman J, Zimmerman R . Group B streptococcal neonatal and infant infections. J Pediatr. 1973; 82(4):707-18. DOI: 10.1016/s0022-3476(73)80604-3. View

WILKINSON H, Facklam R, Wortham E . Distribution by serological type of group B streptococci isolated from a variety of clinical material over a five-year period (with special reference to neonatal sepsis and meningitis). Infect Immun. 1973; 8(2):228-35. PMC: 422837. DOI: 10.1128/iai.8.2.228-235.1973. View

Baker C, Barrett F, Gordon R, YOW M . Suppurative meningitis due to streptococci of Lancefield group B: a study of 33 infants. J Pediatr. 1973; 82(4):724-9. DOI: 10.1016/s0022-3476(73)80606-7. View

10.

Aber R, Allen N, Howell J, Wilkenson H, Facklam R . Nosocomial transmission of group B streptococci. Pediatrics. 1976; 58(3):346-53. View

11.

LERNER P . Meningitis caused by Streptococcus in adults. J Infect Dis. 1975; 131 Suppl:S9-16. DOI: 10.1093/infdis/131.supplement.s9. View

12.

Steere A, Aber R, Warford L, Murphy K, Feeley J, Hayes P . Possible nosocomial transmission of group B streptococci in a newborn nursery. J Pediatr. 1975; 87(5):784-7. DOI: 10.1016/s0022-3476(75)80311-8. View

13.

Anthony B, Concepcion N . Group B streptococcus in a general hospital. J Infect Dis. 1975; 132(5):561-7. DOI: 10.1093/infdis/132.5.561. View

14.

Roe M, TODD J, Favara B . Nonhemolytic group B streptococcal infections. J Pediatr. 1976; 89(1):75-7. DOI: 10.1016/s0022-3476(76)80931-6. View

15.

Hall R, Barnes W, Krishnan L, Harris D, Rhodes P, Fayez J . Antibiotic treatment of parturient women colonized with group B streptococci. Am J Obstet Gynecol. 1976; 124(6):630-4. DOI: 10.1016/0002-9378(76)90065-x. View